Chung DH - Search Results

1

Identification of potent small molecule inhibitors of SARS-CoV-2 entry.

Mediouni S, Mou H, Otsuka Y, Jablonski JA, Adcock RS, Batra L, Chung DH, Rood C, de Vera IMS, Rahaim R Jr, Ullah S, Yu X, Getmanenko YA, Kennedy NM, Wang C, Nguyen TT, Hull M, Chen E, Bannister TD, Baillargeon P, Scampavia L, Farzan M, Valente ST, Spicer TP. Mediouni S, et al. Among authors: chung dh. SLAS Discov. 2022 Jan;27(1):8-19. doi: 10.1016/j.slasd.2021.10.012. Epub 2021 Oct 23. SLAS Discov. 2022. PMID: 35058179 Free PMC article.

2

Phenotypic differences in virulence and immune response in closely related clinical isolates of influenza A 2009 H1N1 pandemic viruses in mice.

Camp JV, Chu YK, Chung DH, McAllister RC, Adcock RS, Gerlach RL, Wiemken TL, Peyrani P, Ramirez JA, Summersgill JT, Jonsson CB. Camp JV, et al. Among authors: chung dh. PLoS One. 2013;8(2):e56602. doi: 10.1371/journal.pone.0056602. Epub 2013 Feb 18. PLoS One. 2013. PMID: 23441208 Free PMC article.

3

Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State.

Chung DH, Golden JE, Adcock RS, Schroeder CE, Chu YK, Sotsky JB, Cramer DE, Chilton PM, Song C, Anantpadma M, Davey RA, Prodhan AI, Yin X, Zhang X. Chung DH, et al. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4552-62. doi: 10.1128/AAC.00282-16. Print 2016 Aug. Antimicrob Agents Chemother. 2016. PMID: 27185801 Free PMC article.

4

Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assay.

Adcock RS, Chu YK, Golden JE, Chung DH. Adcock RS, et al. Among authors: chung dh. Antiviral Res. 2017 Feb;138:47-56. doi: 10.1016/j.antiviral.2016.11.018. Epub 2016 Dec 3. Antiviral Res. 2017. PMID: 27919709

5

Benzamidine ML336 inhibits plus and minus strand RNA synthesis of Venezuelan equine encephalitis virus without affecting host RNA production.

Skidmore AM, Adcock RS, Jonsson CB, Golden JE, Chung DH. Skidmore AM, et al. Among authors: chung dh. Antiviral Res. 2020 Feb;174:104674. doi: 10.1016/j.antiviral.2019.104674. Epub 2019 Dec 6. Antiviral Res. 2020. PMID: 31816348 Free PMC article.

6

Advanced Safety and Genetic Stability in Mice of a Novel DNA-Launched Venezuelan Equine Encephalitis Virus Vaccine with Rearranged Structural Genes.

Johnson DM, Sokoloski KJ, Jokinen JD, Pfeffer TL, Chu YK, Adcock RS, Chung D, Tretyakova I, Pushko P, Lukashevich IS. Johnson DM, et al. Vaccines (Basel). 2020 Mar 2;8(1):114. doi: 10.3390/vaccines8010114. Vaccines (Basel). 2020. PMID: 32121666 Free PMC article.

7

Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids.

Diamond G, Molchanova N, Herlan C, Fortkort JA, Lin JS, Figgins E, Bopp N, Ryan LK, Chung D, Adcock RS, Sherman M, Barron AE. Diamond G, et al. Pharmaceuticals (Basel). 2021 Mar 31;14(4):304. doi: 10.3390/ph14040304. Pharmaceuticals (Basel). 2021. PMID: 33807248 Free PMC article.

8

Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12.

Teng Y, Xu F, Zhang X, Mu J, Sayed M, Hu X, Lei C, Sriwastva M, Kumar A, Sundaram K, Zhang L, Park JW, Chen SY, Zhang S, Yan J, Merchant ML, Zhang X, McClain CJ, Wolfe JK, Adcock RS, Chung D, Palmer KE, Zhang HG. Teng Y, et al. Mol Ther. 2021 Aug 4;29(8):2424-2440. doi: 10.1016/j.ymthe.2021.05.005. Epub 2021 May 11. Mol Ther. 2021. PMID: 33984520 Free PMC article.

9

Induction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients.

Rouchka EC, Chariker JH, Alejandro B, Adcock RS, Singhal R, Ramirez J, Palmer KE, Lasnik AB, Carrico R, Arnold FW, Furmanek S, Zhang M, Wolf LA, Waigel S, Zacharias W, Bordon J, Chung D. Rouchka EC, et al. Sci Rep. 2021 Aug 3;11(1):15715. doi: 10.1038/s41598-021-95197-y. Sci Rep. 2021. PMID: 34344959 Free PMC article.

10

High throughput screening for SARS-CoV-2 helicase inhibitors.

Otsuka Y, Kim E, Krueger A, Shumate J, Wang C, Bdiri B, Ullah S, Park H, Scampavia L, Bannister TD, Chung D, Spicer TP. Otsuka Y, et al. SLAS Discov. 2024 Sep;29(6):100180. doi: 10.1016/j.slasd.2024.100180. Epub 2024 Aug 22. SLAS Discov. 2024. PMID: 39173831 Free article.

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