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Page 1
Magnesium sensing via LFA-1 regulates CD8+ T cell effector function.
Lötscher J, Martí I Líndez AA, Kirchhammer N, Cribioli E, Giordano Attianese GMP, Trefny MP, Lenz M, Rothschild SI, Strati P, Künzli M, Lotter C, Schenk SH, Dehio P, Löliger J, Litzler L, Schreiner D, Koch V, Page N, Lee D, Grählert J, Kuzmin D, Burgener AV, Merkler D, Pless M, Balmer ML, Reith W, Huwyler J, Irving M, King CG, Zippelius A, Hess C. Lötscher J, et al. Among authors: grahlert j. Cell. 2022 Feb 17;185(4):585-602.e29. doi: 10.1016/j.cell.2021.12.039. Epub 2022 Jan 19. Cell. 2022. PMID: 35051368 Free article.
Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function.
Balmer ML, Ma EH, Bantug GR, Grählert J, Pfister S, Glatter T, Jauch A, Dimeloe S, Slack E, Dehio P, Krzyzaniak MA, King CG, Burgener AV, Fischer M, Develioglu L, Belle R, Recher M, Bonilla WV, Macpherson AJ, Hapfelmeier S, Jones RG, Hess C. Balmer ML, et al. Among authors: grahlert j. Immunity. 2016 Jun 21;44(6):1312-24. doi: 10.1016/j.immuni.2016.03.016. Epub 2016 May 17. Immunity. 2016. PMID: 27212436 Free article.
Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8+ T Cells.
Bantug GR, Fischer M, Grählert J, Balmer ML, Unterstab G, Develioglu L, Steiner R, Zhang L, Costa ASH, Gubser PM, Burgener AV, Sauder U, Löliger J, Belle R, Dimeloe S, Lötscher J, Jauch A, Recher M, Hönger G, Hall MN, Romero P, Frezza C, Hess C. Bantug GR, et al. Among authors: grahlert j. Immunity. 2018 Mar 20;48(3):542-555.e6. doi: 10.1016/j.immuni.2018.02.012. Epub 2018 Mar 6. Immunity. 2018. PMID: 29523440 Free PMC article.
Early effector maturation of naïve human CD8+ T cells requires mitochondrial biogenesis.
Fischer M, Bantug GR, Dimeloe S, Gubser PM, Burgener AV, Grählert J, Balmer ML, Develioglu L, Steiner R, Unterstab G, Sauder U, Hoenger G, Hess C. Fischer M, et al. Among authors: grahlert j. Eur J Immunol. 2018 Oct;48(10):1632-1643. doi: 10.1002/eji.201747443. Epub 2018 Aug 7. Eur J Immunol. 2018. PMID: 30028501 Free article.
Memory CD8+ T Cells Balance Pro- and Anti-inflammatory Activity by Reprogramming Cellular Acetate Handling at Sites of Infection.
Balmer ML, Ma EH, Thompson AJ, Epple R, Unterstab G, Lötscher J, Dehio P, Schürch CM, Warncke JD, Perrin G, Woischnig AK, Grählert J, Löliger J, Assmann N, Bantug GR, Schären OP, Khanna N, Egli A, Bubendorf L, Rentsch K, Hapfelmeier S, Jones RG, Hess C. Balmer ML, et al. Among authors: grahlert j. Cell Metab. 2020 Sep 1;32(3):457-467.e5. doi: 10.1016/j.cmet.2020.07.004. Epub 2020 Jul 31. Cell Metab. 2020. PMID: 32738204 Free article.
SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.
Burgener AV, Bantug GR, Meyer BJ, Higgins R, Ghosh A, Bignucolo O, Ma EH, Loeliger J, Unterstab G, Geigges M, Steiner R, Enamorado M, Ivanek R, Hunziker D, Schmidt A, Müller-Durovic B, Grählert J, Epple R, Dimeloe S, Lötscher J, Sauder U, Ebnöther M, Burger B, Heijnen I, Martínez-Cano S, Cantoni N, Brücker R, Kahlert CR, Sancho D, Jones RG, Navarini A, Recher M, Hess C. Burgener AV, et al. Among authors: grahlert j. Nat Immunol. 2019 Oct;20(10):1311-1321. doi: 10.1038/s41590-019-0482-2. Epub 2019 Sep 16. Nat Immunol. 2019. PMID: 31527833