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Mineralocorticoid receptor antagonist treatment of established pulmonary arterial hypertension improves interventricular dependence in the SU5416-hypoxia rat model.
Lu M, Chen LY, Gairhe S, Mazer AJ, Anderson SA, Nelson JNH, Noguchi A, Siddique MAH, Dougherty EJ, Zou Y, Johnston KA, Yu ZX, Wang H, Wang S, Sun J, Solomon SB, Vanderpool RR, Solomon MA, Danner RL, Elinoff JM. Lu M, et al. Among authors: noguchi a. Am J Physiol Lung Cell Mol Physiol. 2022 Mar 1;322(3):L315-L332. doi: 10.1152/ajplung.00238.2021. Epub 2022 Jan 19. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35043674 Free PMC article.
Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter.
Holmström KM, Pan X, Liu JC, Menazza S, Liu J, Nguyen TT, Pan H, Parks RJ, Anderson S, Noguchi A, Springer D, Murphy E, Finkel T. Holmström KM, et al. Among authors: noguchi a. J Mol Cell Cardiol. 2015 Aug;85:178-82. doi: 10.1016/j.yjmcc.2015.05.022. Epub 2015 Jun 6. J Mol Cell Cardiol. 2015. PMID: 26057074 Free PMC article.
Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype.
Flores DJ, Duong T, Brandenberger LO, Mitra A, Shirali A, Johnson JC, Springer D, Noguchi A, Yu ZX, Ebert SN, Ludwig A, Knollmann BC, Levin MD, Pfeifer K. Flores DJ, et al. Among authors: noguchi a. Hum Mol Genet. 2018 May 1;27(9):1533-1544. doi: 10.1093/hmg/ddy060. Hum Mol Genet. 2018. PMID: 29452352 Free PMC article.
X-linked creatine transporter deficiency results in prolonged QTc and increased sudden death risk in humans and disease model.
Levin MD, Bianconi S, Smith A, Cawley NX, Do AD, Hammond D, Grafstein JF, Thurm A, Miller J, Perreault J, Noguchi A, Springer D, Kozel BA, Spurney CF, Wassif CA, Yu ZX, Schulze A, Porter FD, Hannah-Shmouni F. Levin MD, et al. Among authors: noguchi a. Genet Med. 2021 Oct;23(10):1864-1872. doi: 10.1038/s41436-021-01224-8. Epub 2021 May 28. Genet Med. 2021. PMID: 34050321 Free PMC article.
Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.
Ghosh MC, Zhang DL, Jeong SY, Kovtunovych G, Ollivierre-Wilson H, Noguchi A, Tu T, Senecal T, Robinson G, Crooks DR, Tong WH, Ramaswamy K, Singh A, Graham BB, Tuder RM, Yu ZX, Eckhaus M, Lee J, Springer DA, Rouault TA. Ghosh MC, et al. Among authors: noguchi a. Cell Metab. 2013 Feb 5;17(2):271-81. doi: 10.1016/j.cmet.2012.12.016. Cell Metab. 2013. PMID: 23395173 Free PMC article.
PPARγ agonists delay age-associated metabolic disease and extend longevity.
Xu L, Ma X, Verma N, Perie L, Pendse J, Shamloo S, Marie Josephson A, Wang D, Qiu J, Guo M, Ping X, Allen M, Noguchi A, Springer D, Shen F, Liu C, Zhang S, Li L, Li J, Xiao J, Lu J, Du Z, Luo J, Aleman JO, Leucht P, Mueller E. Xu L, et al. Among authors: noguchi a. Aging Cell. 2020 Nov;19(11):e13267. doi: 10.1111/acel.13267. Epub 2020 Nov 21. Aging Cell. 2020. PMID: 33219735 Free PMC article.
Low ambient oxygen prevents atherosclerosis.
Kang JG, Sung HJ, Amar MJ, Pryor M, Remaley AT, Allen MD, Noguchi AC, Springer DA, Kwon J, Chen J, Park JH, Wang PY, Hwang PM. Kang JG, et al. Among authors: noguchi ac. J Mol Med (Berl). 2016 Mar;94(3):277-86. doi: 10.1007/s00109-016-1386-3. Epub 2016 Feb 2. J Mol Med (Berl). 2016. PMID: 26830628 Free PMC article.
697 results