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Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity.
Chakraborty S, Gonzalez JC, Sievers BL, Mallajosyula V, Chakraborty S, Dubey M, Ashraf U, Cheng BY, Kathale N, Tran KQT, Scallan C, Sinnott A, Cassidy A, Chen ST, Gelbart T, Gao F, Golan Y, Ji X, Kim-Schulze S, Prahl M, Gaw SL, Gnjatic S, Marron TU, Merad M, Arunachalam PS, Boyd SD, Davis MM, Holubar M, Khosla C, Maecker HT, Maldonado Y, Mellins ED, Nadeau KC, Pulendran B, Singh U, Subramanian A, Utz PJ, Sherwood R, Zhang S, Jagannathan P, Tan GS, Wang TT. Chakraborty S, et al. Among authors: gonzalez jc. Sci Transl Med. 2022 Mar 9;14(635):eabm7853. doi: 10.1126/scitranslmed.abm7853. Epub 2022 Mar 9. Sci Transl Med. 2022. PMID: 35040666 Free PMC article.
Proinflammatory IgG Fc structures in patients with severe COVID-19.
Chakraborty S, Gonzalez J, Edwards K, Mallajosyula V, Buzzanco AS, Sherwood R, Buffone C, Kathale N, Providenza S, Xie MM, Andrews JR, Blish CA, Singh U, Dugan H, Wilson PC, Pham TD, Boyd SD, Nadeau KC, Pinsky BA, Zhang S, Memoli MJ, Taubenberger JK, Morales T, Schapiro JM, Tan GS, Jagannathan P, Wang TT. Chakraborty S, et al. medRxiv [Preprint]. 2020 Nov 10:2020.05.15.20103341. doi: 10.1101/2020.05.15.20103341. medRxiv. 2020. Update in: Nat Immunol. 2021 Jan;22(1):67-73. doi: 10.1038/s41590-020-00828-7 PMID: 32511463 Free PMC article. Updated. Preprint.
Proinflammatory IgG Fc structures in patients with severe COVID-19.
Chakraborty S, Gonzalez J, Edwards K, Mallajosyula V, Buzzanco AS, Sherwood R, Buffone C, Kathale N, Providenza S, Xie MM, Andrews JR, Blish CA, Singh U, Dugan H, Wilson PC, Pham TD, Boyd SD, Nadeau KC, Pinsky BA, Zhang S, Memoli MJ, Taubenberger JK, Morales T, Schapiro JM, Tan GS, Jagannathan P, Wang TT. Chakraborty S, et al. Nat Immunol. 2021 Jan;22(1):67-73. doi: 10.1038/s41590-020-00828-7. Epub 2020 Nov 9. Nat Immunol. 2021. PMID: 33169014 Free PMC article.
Structurally and functionally distinct early antibody responses predict COVID-19 disease trajectory and mRNA vaccine response.
Chakraborty S, Gonzalez JC, Sievers BL, Mallajosyula V, Chakraborty S, Dubey M, Ashraf U, Cheng BY, Kathale N, Tran KQT, Scallan C, Sinnott A, Cassidy A, Chen ST, Gelbart T, Gao F, Golan Y, Ji X, Kim-Schulze S, Prahl M, Gaw SL, Gnjatic S, Marron TU, Merad M, Arunachalam PS, Boyd SD, Davis MM, Holubar M, Khosla C, Maecker HT, Maldonado Y, Mellins ED, Nadeau KC, Pulendran B, Singh U, Subramanian A, Utz PJ, Sherwood R, Zhang S, Jagannathan P, Tan GS, Wang TT. Chakraborty S, et al. Among authors: gonzalez jc. bioRxiv [Preprint]. 2021 Dec 27:2021.05.25.445649. doi: 10.1101/2021.05.25.445649. bioRxiv. 2021. PMID: 34075376 Free PMC article. Preprint.
Assessment of Allergic and Anaphylactic Reactions to mRNA COVID-19 Vaccines With Confirmatory Testing in a US Regional Health System.
Warren CM, Snow TT, Lee AS, Shah MM, Heider A, Blomkalns A, Betts B, Buzzanco AS, Gonzalez J, Chinthrajah RS, Do E, Chang I, Dunham D, Lee G, O'Hara R, Park H, Shamji MH, Schilling L, Sindher SB, Sisodiya D, Smith E, Tsai M, Galli SJ, Akdis C, Nadeau KC. Warren CM, et al. JAMA Netw Open. 2021 Sep 1;4(9):e2125524. doi: 10.1001/jamanetworkopen.2021.25524. JAMA Netw Open. 2021. PMID: 34533570 Free PMC article.
Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses.
Sievers BL, Chakraborty S, Xue Y, Gelbart T, Gonzalez JC, Cassidy AG, Golan Y, Prahl M, Gaw SL, Arunachalam PS, Blish CA, Boyd SD, Davis MM, Jagannathan P, Nadeau KC, Pulendran B, Singh U, Scheuermann RH, Frieman MB, Vashee S, Wang TT, Tan GS. Sievers BL, et al. Among authors: gonzalez jc. Sci Transl Med. 2022 Mar 2;14(634):eabn7842. doi: 10.1126/scitranslmed.abn7842. Epub 2022 Mar 2. Sci Transl Med. 2022. PMID: 35025672 Free PMC article.
Harnessing IgG Fc glycosylation for clinical benefit.
Archer EJ, Gonzalez JC, Ghosh D, Mellins ED, Wang TT. Archer EJ, et al. Among authors: gonzalez jc. Curr Opin Immunol. 2022 Aug;77:102231. doi: 10.1016/j.coi.2022.102231. Epub 2022 Jul 4. Curr Opin Immunol. 2022. PMID: 35797920 Free PMC article. Review.
Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8+ T cell responses post SARS-CoV-2 infection.
Gao F, Mallajosyula V, Arunachalam PS, van der Ploeg K, Manohar M, Röltgen K, Yang F, Wirz O, Hoh R, Haraguchi E, Lee JY, Willis R, Ramachandiran V, Li J, Kathuria KR, Li C, Lee AS, Shah MM, Sindher SB, Gonzalez J, Altman JD, Wang TT, Boyd SD, Pulendran B, Jagannathan P, Nadeau KC, Davis MM. Gao F, et al. Immunity. 2023 Apr 11;56(4):864-878.e4. doi: 10.1016/j.immuni.2023.03.005. Epub 2023 Mar 16. Immunity. 2023. PMID: 36996809 Free PMC article.
280 results