Wei H - Search Results

1

Novel PHD2/HDACs hybrid inhibitors protect against cisplatin-induced acute kidney injury.

Wei H, Gou W, Gao J, Ning H, Song Y, Li D, Qin Y, Hou W, Li Y. Wei H, et al. Eur J Med Chem. 2022 Feb 15;230:114115. doi: 10.1016/j.ejmech.2022.114115. Epub 2022 Jan 11. Eur J Med Chem. 2022. PMID: 35033824

2

Design, synthesis and biological evaluation of novel 4-anilinoquinazoline derivatives as hypoxia-selective EGFR and VEGFR-2 dual inhibitors.

Wei H, Duan Y, Gou W, Cui J, Ning H, Li D, Qin Y, Liu Q, Li Y. Wei H, et al. Eur J Med Chem. 2019 Nov 1;181:111552. doi: 10.1016/j.ejmech.2019.07.055. Epub 2019 Jul 24. Eur J Med Chem. 2019. PMID: 31387063

3

Discovery of novel triazole compounds as selective IL-1β releasement inhibitors.

Mu R, Zhou Y, Chen L, Wei H, Yu J, Gou W, Ye C, Hou W, Li Y, Zhu L. Mu R, et al. Among authors: wei h. Bioorg Med Chem Lett. 2021 Dec 1;53:128415. doi: 10.1016/j.bmcl.2021.128415. Epub 2021 Oct 16. Bioorg Med Chem Lett. 2021. PMID: 34662706

4

Discovery and radiosensitization research of ursolic acid derivatives as SENP1 inhibitors.

Wei H, Guo J, Sun X, Gou W, Ning H, Fang Z, Liu Q, Hou W, Li Y. Wei H, et al. Eur J Med Chem. 2022 Jan 5;227:113918. doi: 10.1016/j.ejmech.2021.113918. Epub 2021 Oct 14. Eur J Med Chem. 2022. PMID: 34688014

5

Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress.

Gou W, Luo N, Wei H, Wu H, Yu X, Duan Y, Bi C, Ning H, Hou W, Li Y. Gou W, et al. Among authors: wei h. Pharm Biol. 2020 Dec;58(1):707-715. doi: 10.1080/13880209.2020.1794013. Pharm Biol. 2020. PMID: 32726164 Free PMC article.

6

Recent progress in small-molecule inhibitors for critical therapeutic targets of necroptosis.

Fang Z, Wei H, Gou W, Chen L, Bi C, Hou W, Li Y. Fang Z, et al. Among authors: wei h. Future Med Chem. 2021 May;13(9):817-837. doi: 10.4155/fmc-2020-0386. Epub 2021 Apr 13. Future Med Chem. 2021. PMID: 33845591 Review.

7

Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.

Gou W, Luo N, Yu B, Wu H, Wu S, Tian C, Guo J, Ning H, Bi C, Wei H, Hou W, Li Y. Gou W, et al. Among authors: wei h. Int J Biol Sci. 2022 Mar 21;18(6):2639-2651. doi: 10.7150/ijbs.67166. eCollection 2022. Int J Biol Sci. 2022. PMID: 35414766 Free PMC article.

8

Discovery of Natural Ursane-type SENP1 Inhibitors and the Platinum Resistance Reversal Activity Against Human Ovarian Cancer Cells: A Structure-Activity Relationship Study.

Wei H, Guo J, Sun X, Gou W, Ning H, Shang H, Liu Q, Hou W, Li Y. Wei H, et al. J Nat Prod. 2022 May 27;85(5):1248-1255. doi: 10.1021/acs.jnatprod.1c01166. Epub 2022 May 2. J Nat Prod. 2022. PMID: 35500202 Review.

9

Design and Synthesis of Vandetanib Derivatives Containing Nitroimidazole Groups as Tyrosine Kinase Inhibitors in Normoxia and Hypoxia.

Wei H, Li D, Yang X, Shang H, Fan S, Li Y, Song D. Wei H, et al. Molecules. 2016 Dec 14;21(12):1693. doi: 10.3390/molecules21121693. Molecules. 2016. PMID: 27983649 Free PMC article.

10

Acetyl-CoA carboxylase (ACC) as a therapeutic target for metabolic syndrome and recent developments in ACC1/2 inhibitors.

Chen L, Duan Y, Wei H, Ning H, Bi C, Zhao Y, Qin Y, Li Y. Chen L, et al. Among authors: wei h. Expert Opin Investig Drugs. 2019 Oct;28(10):917-930. doi: 10.1080/13543784.2019.1657825. Epub 2019 Aug 29. Expert Opin Investig Drugs. 2019. PMID: 31430206 Review.

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