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HLA-independent T cell receptors for targeting tumors with low antigen density.
Mansilla-Soto J, Eyquem J, Haubner S, Hamieh M, Feucht J, Paillon N, Zucchetti AE, Li Z, Sjöstrand M, Lindenbergh PL, Saetersmoen M, Dobrin A, Maurin M, Iyer A, Garcia Angus A, Miele MM, Zhao Z, Giavridis T, van der Stegen SJC, Tamzalit F, Rivière I, Huse M, Hendrickson RC, Hivroz C, Sadelain M. Mansilla-Soto J, et al. Among authors: hamieh m. Nat Med. 2022 Feb;28(2):345-352. doi: 10.1038/s41591-021-01621-1. Epub 2022 Jan 13. Nat Med. 2022. PMID: 35027758 Free PMC article.
The pharmacology of second-generation chimeric antigen receptors.
van der Stegen SJ, Hamieh M, Sadelain M. van der Stegen SJ, et al. Among authors: hamieh m. Nat Rev Drug Discov. 2015 Jul;14(7):499-509. doi: 10.1038/nrd4597. Nat Rev Drug Discov. 2015. PMID: 26129802 Free PMC article. Review.
T-cell responses against CD19+ pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts.
Feucht J, Kayser S, Gorodezki D, Hamieh M, Döring M, Blaeschke F, Schlegel P, Bösmüller H, Quintanilla-Fend L, Ebinger M, Lang P, Handgretinger R, Feuchtinger T. Feucht J, et al. Among authors: hamieh m. Oncotarget. 2016 Nov 22;7(47):76902-76919. doi: 10.18632/oncotarget.12357. Oncotarget. 2016. PMID: 27708227 Free PMC article.
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection.
Eyquem J, Mansilla-Soto J, Giavridis T, van der Stegen SJ, Hamieh M, Cunanan KM, Odak A, Gönen M, Sadelain M. Eyquem J, et al. Among authors: hamieh m. Nature. 2017 Mar 2;543(7643):113-117. doi: 10.1038/nature21405. Epub 2017 Feb 22. Nature. 2017. PMID: 28225754 Free PMC article.
40 results