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Page 1
THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer.
Blomme A, Peter C, Mui E, Rodriguez Blanco G, An N, Mason LM, Jamieson LE, McGregor GH, Lilla S, Ntala C, Patel R, Thiry M, Kung SHY, Leclercq M, Ford CA, Rushworth LK, McGarry DJ, Mason S, Repiscak P, Nixon C, Salji MJ, Markert E, MacKay GM, Kamphorst JJ, Graham D, Faulds K, Fazli L, Gleave ME, Avezov E, Edwards J, Yin H, Sumpton D, Blyth K, Close P, Murphy DJ, Zanivan S, Leung HY. Blomme A, et al. Among authors: rushworth lk. EMBO Mol Med. 2022 Mar 7;14(3):e14764. doi: 10.15252/emmm.202114764. Epub 2022 Jan 11. EMBO Mol Med. 2022. PMID: 35014179 Free PMC article.
SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer.
Martinez RS, Salji MJ, Rushworth L, Ntala C, Rodriguez Blanco G, Hedley A, Clark W, Peixoto P, Hervouet E, Renaude E, Kung SHY, Galbraith LCA, Nixon C, Lilla S, MacKay GM, Fazli L, Gaughan L, Sumpton D, Gleave ME, Zanivan S, Blomme A, Leung HY. Martinez RS, et al. Cancer Res. 2021 Jul 1;81(13):3664-3678. doi: 10.1158/0008-5472.CAN-20-3694. Epub 2021 May 13. Cancer Res. 2021. PMID: 33985973 Free article.
Activation of β-Catenin Cooperates with Loss of Pten to Drive AR-Independent Castration-Resistant Prostate Cancer.
Patel R, Brzezinska EA, Repiscak P, Ahmad I, Mui E, Gao M, Blomme A, Harle V, Tan EH, Malviya G, Mrowinska A, Loveridge CJ, Rushworth LK, Edwards J, Ntala C, Nixon C, Hedley A, Mackay G, Tardito S, Sansom OJ, Leung HY. Patel R, et al. Among authors: rushworth lk. Cancer Res. 2020 Feb 1;80(3):576-590. doi: 10.1158/0008-5472.CAN-19-1684. Epub 2019 Nov 12. Cancer Res. 2020. PMID: 31719098 Free article.
Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression.
Patel R, Ford CA, Rodgers L, Rushworth LK, Fleming J, Mui E, Zhang T, Watson D, Lynch V, Mackay G, Sumpton D, Sansom OJ, Vande Voorde J, Leung HY. Patel R, et al. Among authors: rushworth lk. Cancer Res. 2022 Jul 18;82(14):2565-2575. doi: 10.1158/0008-5472.CAN-21-1301. Cancer Res. 2022. PMID: 35675421 Free PMC article.
Phase II proof-of-concept study of atorvastatin in castration-resistant prostate cancer.
Rushworth LK, Loveridge C, Salji M, MacLeod M, Mui E, Sumpton D, Neilson M, Hedley A, Alexander L, McCartney E, Patel R, Wallace J, Delles C, Jones R, Leung HY. Rushworth LK, et al. BJU Int. 2023 Feb;131(2):236-243. doi: 10.1111/bju.15851. Epub 2022 Aug 12. BJU Int. 2023. PMID: 35844167 Free PMC article. Clinical Trial.
Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6.
Kidger AM, Saville MK, Rushworth LK, Davidson J, Stellzig J, Ono M, Kuebelsbeck LA, Janssen KP, Holzmann B, Morton JP, Sansom OJ, Caunt CJ, Keyse SM. Kidger AM, et al. Among authors: rushworth lk. Oncogene. 2022 May;41(20):2811-2823. doi: 10.1038/s41388-022-02302-0. Epub 2022 Apr 13. Oncogene. 2022. PMID: 35418690 Free PMC article.
Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression.
Rushworth LK, Kidger AM, Delavaine L, Stewart G, van Schelven S, Davidson J, Bryant CJ, Caddye E, East P, Caunt CJ, Keyse SM. Rushworth LK, et al. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18267-72. doi: 10.1073/pnas.1420159112. Epub 2014 Dec 8. Proc Natl Acad Sci U S A. 2014. PMID: 25489104 Free PMC article.
14 results