Schaeffeler E - Search Results

1

How paediatric drug development and use could benefit from OMICs: A c4c expert group white paper.

Neumann E, Schreeck F, Herberg J, Jacqz Aigrain E, Maitland-van der Zee AH, Pérez-Martínez A, Hawcutt DB, Schaeffeler E, Rane A, de Wildt SN, Schwab M. Neumann E, et al. Among authors: schaeffeler e. Br J Clin Pharmacol. 2022 Dec;88(12):5017-5033. doi: 10.1111/bcp.15216. Epub 2022 Feb 9. Br J Clin Pharmacol. 2022. PMID: 34997627 Free article. Review.

2

High-throughput genotyping of thiopurine S-methyltransferase by denaturing HPLC.

Schaeffeler E, Lang T, Zanger UM, Eichelbaum M, Schwab M. Schaeffeler E, et al. Clin Chem. 2001 Mar;47(3):548-55. Clin Chem. 2001. PMID: 11238310

3

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

Cascorbi I, Gerloff T, Johne A, Meisel C, Hoffmeyer S, Schwab M, Schaeffeler E, Eichelbaum M, Brinkmann U, Roots I. Cascorbi I, et al. Among authors: schaeffeler e. Clin Pharmacol Ther. 2001 Mar;69(3):169-74. doi: 10.1067/mcp.2001.114164. Clin Pharmacol Ther. 2001. PMID: 11240981 Clinical Trial.

4

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.

Drescher S, Schaeffeler E, Hitzl M, Hofmann U, Schwab M, Brinkmann U, Eichelbaum M, Fromm MF. Drescher S, et al. Among authors: schaeffeler e. Br J Clin Pharmacol. 2002 May;53(5):526-34. doi: 10.1046/j.1365-2125.2002.01591.x. Br J Clin Pharmacol. 2002. PMID: 11994059 Free PMC article. Clinical Trial.

5

Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease.

Furuno T, Landi MT, Ceroni M, Caporaso N, Bernucci I, Nappi G, Martignoni E, Schaeffeler E, Eichelbaum M, Schwab M, Zanger UM. Furuno T, et al. Among authors: schaeffeler e. Pharmacogenetics. 2002 Oct;12(7):529-34. doi: 10.1097/00008571-200210000-00004. Pharmacogenetics. 2002. PMID: 12360103

6

Pharmacokinetic modelling of morphine, morphine-3-glucuronide and morphine-6-glucuronide in plasma and cerebrospinal fluid of neurosurgical patients after short-term infusion of morphine.

Meineke I, Freudenthaler S, Hofmann U, Schaeffeler E, Mikus G, Schwab M, Prange HW, Gleiter CH, Brockmöller J. Meineke I, et al. Among authors: schaeffeler e. Br J Clin Pharmacol. 2002 Dec;54(6):592-603. doi: 10.1046/j.1365-2125.2002.t01-1-01689.x. Br J Clin Pharmacol. 2002. PMID: 12492606 Free article.

7

[Therapy of chronic inflammatory bowel diseases with azathioprine, 6-mercaptopurine and 6-thioguanine. Clinico-pharmacologic aspects].

Schwab M, Herrlinger K, Schaeffeler E, Stange EF. Schwab M, et al. Among authors: schaeffeler e. Dtsch Med Wochenschr. 2003 Feb 21;128(8):378-85. doi: 10.1055/s-2003-37378. Dtsch Med Wochenschr. 2003. PMID: 12594624 Review. German. No abstract available.

8

CYP2D6 genotyping strategy based on gene copy number determination by TaqMan real-time PCR.

Schaeffeler E, Schwab M, Eichelbaum M, Zanger UM. Schaeffeler E, et al. Hum Mutat. 2003 Dec;22(6):476-85. doi: 10.1002/humu.10280. Hum Mutat. 2003. PMID: 14635107

9

Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).

Hitzl M, Schaeffeler E, Hocher B, Slowinski T, Halle H, Eichelbaum M, Kaufmann P, Fritz P, Fromm MF, Schwab M. Hitzl M, et al. Among authors: schaeffeler e. Pharmacogenetics. 2004 May;14(5):309-18. doi: 10.1097/00008571-200405000-00006. Pharmacogenetics. 2004. PMID: 15115917

10

Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants.

Schaeffeler E, Fischer C, Brockmeier D, Wernet D, Moerike K, Eichelbaum M, Zanger UM, Schwab M. Schaeffeler E, et al. Pharmacogenetics. 2004 Jul;14(7):407-17. doi: 10.1097/01.fpc.0000114745.08559.db. Pharmacogenetics. 2004. PMID: 15226673

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