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CXCL4 drives fibrosis by promoting several key cellular and molecular processes.
Affandi AJ, Carvalheiro T, Ottria A, de Haan JJ, Brans MAD, Brandt MM, Tieland RG, Lopes AP, Fernández BM, Bekker CPJ, van der Linden M, Zimmermann M, Giovannone B, Wichers CGK, Garcia S, de Kok M, Stifano G, Xu YJ, Kowalska MA, Waasdorp M, Cheng C, Gibbs S, de Jager SCA, van Roon JAG, Radstake TRDJ, Marut W. Affandi AJ, et al. Among authors: marut w. Cell Rep. 2022 Jan 4;38(1):110189. doi: 10.1016/j.celrep.2021.110189. Cell Rep. 2022. PMID: 34986347 Free article.
Serum microRNA screening and functional studies reveal miR-483-5p as a potential driver of fibrosis in systemic sclerosis.
Chouri E, Servaas NH, Bekker CPJ, Affandi AJ, Cossu M, Hillen MR, Angiolilli C, Mertens JS, van den Hoogen LL, Silva-Cardoso S, van der Kroef M, Vazirpanah N, Wichers CGK, Carvalheiro T, Blokland SLM, Giovannone B, Porretti L, Marut W, Vigone B, van Roon JAG, Beretta L, Rossato M, Radstake TRDJ. Chouri E, et al. Among authors: marut w. J Autoimmun. 2018 May;89:162-170. doi: 10.1016/j.jaut.2017.12.015. Epub 2018 Jan 20. J Autoimmun. 2018. PMID: 29371048 Free article.
Induction of Inflammation and Fibrosis by Semaphorin 4A in Systemic Sclerosis.
Carvalheiro T, Affandi AJ, Malvar-Fernández B, Dullemond I, Cossu M, Ottria A, Mertens JS, Giovannone B, Bonte-Mineur F, Kok MR, Marut W, Reedquist KA, Radstake TR, García S. Carvalheiro T, et al. Among authors: marut w. Arthritis Rheumatol. 2019 Oct;71(10):1711-1722. doi: 10.1002/art.40915. Epub 2019 Aug 27. Arthritis Rheumatol. 2019. PMID: 31012544 Free PMC article.
Low RUNX3 expression alters dendritic cell function in patients with systemic sclerosis and contributes to enhanced fibrosis.
Affandi AJ, Carvalheiro T, Ottria A, Broen JC, Bossini-Castillo L, Tieland RG, Bon LV, Chouri E, Rossato M, Mertens JS, Garcia S, Pandit A, de Kroon LM, Christmann RB, Martin J, van Roon JA, Radstake TR, Marut W. Affandi AJ, et al. Among authors: marut w. Ann Rheum Dis. 2019 Sep;78(9):1249-1259. doi: 10.1136/annrheumdis-2018-214991. Epub 2019 May 24. Ann Rheum Dis. 2019. PMID: 31126957
CXCL4 Links Inflammation and Fibrosis by Reprogramming Monocyte-Derived Dendritic Cells in vitro.
Silva-Cardoso SC, Tao W, Angiolilli C, Lopes AP, Bekker CPJ, Devaprasad A, Giovannone B, van Laar J, Cossu M, Marut W, Hack E, de Boer RJ, Boes M, Radstake TRDJ, Pandit A. Silva-Cardoso SC, et al. Among authors: marut w. Front Immunol. 2020 Sep 17;11:2149. doi: 10.3389/fimmu.2020.02149. eCollection 2020. Front Immunol. 2020. PMID: 33042127 Free PMC article.
34 results