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Page 1
Broadly neutralizing antibodies target a haemagglutinin anchor epitope.
Guthmiller JJ, Han J, Utset HA, Li L, Lan LY, Henry C, Stamper CT, McMahon M, O'Dell G, Fernández-Quintero ML, Freyn AW, Amanat F, Stovicek O, Gentles L, Richey ST, de la Peña AT, Rosado V, Dugan HL, Zheng NY, Tepora ME, Bitar DJ, Changrob S, Strohmeier S, Huang M, García-Sastre A, Liedl KR, Bloom JD, Nachbagauer R, Palese P, Krammer F, Coughlan L, Ward AB, Wilson PC. Guthmiller JJ, et al. Among authors: rosado v. Nature. 2022 Feb;602(7896):314-320. doi: 10.1038/s41586-021-04356-8. Epub 2021 Dec 23. Nature. 2022. PMID: 34942633 Free PMC article.
Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to stalk epitopes.
Freyn AW, Han J, Guthmiller JJ, Bailey MJ, Neu K, Turner HL, Rosado VC, Chromikova V, Huang M, Strohmeier S, Liu STH, Simon V, Krammer F, Ward AB, Palese P, Wilson PC, Nachbagauer R. Freyn AW, et al. Among authors: rosado vc. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2018102118. doi: 10.1073/pnas.2018102118. Proc Natl Acad Sci U S A. 2021. PMID: 33593910 Free PMC article.
A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses.
Sun W, Liu Y, Amanat F, González-Domínguez I, McCroskery S, Slamanig S, Coughlan L, Rosado V, Lemus N, Jangra S, Rathnasinghe R, Schotsaert M, Martinez JL, Sano K, Mena I, Innis BL, Wirachwong P, Thai DH, Oliveira RDN, Scharf R, Hjorth R, Raghunandan R, Krammer F, García-Sastre A, Palese P. Sun W, et al. Among authors: rosado v. Nat Commun. 2021 Oct 27;12(1):6197. doi: 10.1038/s41467-021-26499-y. Nat Commun. 2021. PMID: 34707161 Free PMC article.
An influenza hemagglutinin stem nanoparticle vaccine induces cross-group 1 neutralizing antibodies in healthy adults.
Widge AT, Hofstetter AR, Houser KV, Awan SF, Chen GL, Burgos Florez MC, Berkowitz NM, Mendoza F, Hendel CS, Holman LA, Gordon IJ, Apte P, Liang CJ, Gaudinski MR, Coates EE, Strom L, Wycuff D, Vazquez S, Stein JA, Gall JG, Adams WC, Carlton K, Gillespie RA, Creanga A, Crank MC, Andrews SF, Castro M, Serebryannyy LA, Narpala SR, Hatcher C, Lin BC, O'Connell S, Freyn AW, Rosado VC, Nachbagauer R, Palese P, Kanekiyo M, McDermott AB, Koup RA, Dropulic LK, Graham BS, Mascola JR, Ledgerwood JE; VRC 321 study team. Widge AT, et al. Among authors: rosado vc. Sci Transl Med. 2023 Apr 19;15(692):eade4790. doi: 10.1126/scitranslmed.ade4790. Epub 2023 Apr 19. Sci Transl Med. 2023. PMID: 37075129 Free PMC article. Clinical Trial.
Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.
Ray R, Nait Mohamed FA, Maurer DP, Huang J, Alpay BA, Ronsard L, Xie Z, Han J, Fernandez-Quintero M, Phan QA, Ursin RL, Vu M, Kirsch KH, Prum T, Rosado VC, Bracamonte-Moreno T, Okonkwo V, Bals J, McCarthy C, Nair U, Kanekiyo M, Ward AB, Schmidt AG, Batista FD, Lingwood D. Ray R, et al. Among authors: rosado vc. Immunity. 2024 May 14;57(5):1141-1159.e11. doi: 10.1016/j.immuni.2024.03.022. Epub 2024 Apr 25. Immunity. 2024. PMID: 38670113 Free PMC article.
Stratified analysis identifies HIF-2α as a therapeutic target for highly immune-infiltrated melanomas.
Huang AY, Burke KP, Porter R, Meiger L, Fatouros P, Yang J, Robitschek E, Vokes N, Ricker C, Rosado V, Tarantino G, Chen J, Aprati TJ, Glettig MC, He Y, Wang C, Fu D, Ho LL, Galani K, Freeman GJ, Buchbinder EI, Stephen Hodi F, Kellis M, Boland GM, Sharpe AH, Liu D. Huang AY, et al. Among authors: rosado v. bioRxiv [Preprint]. 2024 Oct 30:2024.10.29.620300. doi: 10.1101/2024.10.29.620300. bioRxiv. 2024. PMID: 39554029 Free PMC article. Preprint.
Divergent metabolic phenotypes in two genetic syndromes of low insulin secretion.
Guevara-Aguirre J, Rosenbloom AL, Guevara A, Atkinson MA, Williams MD, Terán E, Posgai AL, Guevara C, Rosado V, Gavilanes AWD, Wasserfall CH. Guevara-Aguirre J, et al. Among authors: rosado v. Diabetes Res Clin Pract. 2023 Feb;196:110228. doi: 10.1016/j.diabres.2022.110228. Epub 2022 Dec 19. Diabetes Res Clin Pract. 2023. PMID: 36549505 Free PMC article.
38 results