Gewin L - Search Results

1

DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3.

Borza CM, Bolas G, Bock F, Zhang X, Akabogu FC, Zhang MZ, de Caestecker M, Yang M, Yang H, Lee E, Gewin L, Fogo AB, McDonald WH, Zent R, Pozzi A. Borza CM, et al. Among authors: gewin l. JCI Insight. 2022 Feb 8;7(3):e150887. doi: 10.1172/jci.insight.150887. JCI Insight. 2022. PMID: 34941574 Free PMC article.

2

Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity.

Pozzi A, Jarad G, Moeckel GW, Coffa S, Zhang X, Gewin L, Eremina V, Hudson BG, Borza DB, Harris RC, Holzman LB, Phillips CL, Fassler R, Quaggin SE, Miner JH, Zent R. Pozzi A, et al. Among authors: gewin l. Dev Biol. 2008 Apr 15;316(2):288-301. doi: 10.1016/j.ydbio.2008.01.022. Epub 2008 Jan 31. Dev Biol. 2008. PMID: 18328474 Free PMC article.

3

beta1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity.

Zhang X, Mernaugh G, Yang DH, Gewin L, Srichai MB, Harris RC, Iturregui JM, Nelson RD, Kohan DE, Abrahamson D, Fässler R, Yurchenco P, Pozzi A, Zent R. Zhang X, et al. Among authors: gewin l. Development. 2009 Oct;136(19):3357-66. doi: 10.1242/dev.036269. Epub 2009 Aug 26. Development. 2009. PMID: 19710172 Free PMC article.

4

TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis.

Gewin L, Bulus N, Mernaugh G, Moeckel G, Harris RC, Moses HL, Pozzi A, Zent R. Gewin L, et al. J Am Soc Nephrol. 2010 Aug;21(8):1334-43. doi: 10.1681/ASN.2010020147. Epub 2010 Jun 24. J Am Soc Nephrol. 2010. PMID: 20576806 Free PMC article.

5

Membrane-type 4 matrix metalloproteinase (MT4-MMP) modulates water homeostasis in mice.

Srichai MB, Colleta H, Gewin L, Matrisian L, Abel TW, Koshikawa N, Seiki M, Pozzi A, Harris RC, Zent R. Srichai MB, et al. Among authors: gewin l. PLoS One. 2011 Feb 11;6(2):e17099. doi: 10.1371/journal.pone.0017099. PLoS One. 2011. PMID: 21347258 Free PMC article.

6

How does TGF-β mediate tubulointerstitial fibrosis?

Gewin L, Zent R. Gewin L, et al. Semin Nephrol. 2012 May;32(3):228-35. doi: 10.1016/j.semnephrol.2012.04.001. Semin Nephrol. 2012. PMID: 22835453 Free PMC article. Review.

7

Deleting the TGF-β receptor attenuates acute proximal tubule injury.

Gewin L, Vadivelu S, Neelisetty S, Srichai MB, Paueksakon P, Pozzi A, Harris RC, Zent R. Gewin L, et al. J Am Soc Nephrol. 2012 Dec;23(12):2001-11. doi: 10.1681/ASN.2012020139. Epub 2012 Nov 15. J Am Soc Nephrol. 2012. PMID: 23160515 Free PMC article.

8

Role of epoxyeicosatrienoic acids (EETs) in mediation of dopamine's effects in the kidney.

Zhang MZ, Wang Y, Yao B, Gewin L, Wei S, Capdevila JH, Harris RC. Zhang MZ, et al. Among authors: gewin l. Am J Physiol Renal Physiol. 2013 Dec 15;305(12):F1680-6. doi: 10.1152/ajprenal.00409.2013. Epub 2013 Oct 23. Am J Physiol Renal Physiol. 2013. PMID: 24154693 Free PMC article.

9

Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling.

Chen X, Wang H, Liao HJ, Hu W, Gewin L, Mernaugh G, Zhang S, Zhang ZY, Vega-Montoto L, Vanacore RM, Fässler R, Zent R, Pozzi A. Chen X, et al. Among authors: gewin l. J Clin Invest. 2014 Aug;124(8):3295-310. doi: 10.1172/JCI71668. Epub 2014 Jul 1. J Clin Invest. 2014. PMID: 24983314 Free PMC article.

10

Renal fibrosis is not reduced by blocking transforming growth factor-β signaling in matrix-producing interstitial cells.

Neelisetty S, Alford C, Reynolds K, Woodbury L, Nlandu-Khodo S, Yang H, Fogo AB, Hao CM, Harris RC, Zent R, Gewin L. Neelisetty S, et al. Among authors: gewin l. Kidney Int. 2015 Sep;88(3):503-14. doi: 10.1038/ki.2015.51. Epub 2015 Mar 11. Kidney Int. 2015. PMID: 25760325 Free PMC article.

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