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Repeat Expansion Disease Models.
Ueyama M, Nagai Y. Ueyama M, et al. Among authors: nagai y. Adv Exp Med Biol. 2018;1076:63-78. doi: 10.1007/978-981-13-0529-0_5. Adv Exp Med Biol. 2018. PMID: 29951815 Review.
FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD.
Fujino Y, Ueyama M, Ishiguro T, Ozawa D, Ito H, Sugiki T, Murata A, Ishiguro A, Gendron T, Mori K, Tokuda E, Taminato T, Konno T, Koyama A, Kawabe Y, Takeuchi T, Furukawa Y, Fujiwara T, Ikeda M, Mizuno T, Mochizuki H, Mizusawa H, Wada K, Ishikawa K, Onodera O, Nakatani K, Petrucelli L, Taguchi H, Nagai Y. Fujino Y, et al. Among authors: nagai y. Elife. 2023 Jul 18;12:RP84338. doi: 10.7554/eLife.84338. Elife. 2023. PMID: 37461319 Free PMC article.
Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD.
Ueda T, Takeuchi T, Fujikake N, Suzuki M, Minakawa EN, Ueyama M, Fujino Y, Kimura N, Nagano S, Yokoseki A, Onodera O, Mochizuki H, Mizuno T, Wada K, Nagai Y. Ueda T, et al. Among authors: nagai y. Acta Neuropathol Commun. 2024 Feb 4;12(1):20. doi: 10.1186/s40478-024-01729-8. Acta Neuropathol Commun. 2024. PMID: 38311779 Free PMC article.
Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31.
Ishiguro T, Sato N, Ueyama M, Fujikake N, Sellier C, Kanegami A, Tokuda E, Zamiri B, Gall-Duncan T, Mirceta M, Furukawa Y, Yokota T, Wada K, Taylor JP, Pearson CE, Charlet-Berguerand N, Mizusawa H, Nagai Y, Ishikawa K. Ishiguro T, et al. Among authors: nagai y. Neuron. 2017 Apr 5;94(1):108-124.e7. doi: 10.1016/j.neuron.2017.02.046. Epub 2017 Mar 23. Neuron. 2017. PMID: 28343865 Free PMC article.
2,978 results