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Engineering for an HPV 9-valent vaccine candidate using genomic constitutive over-expression and low lipopolysaccharide levels in Escherichia coli cells.
Wang K, Zhou L, Chen T, Li Q, Li J, Liu L, Li Y, Sun J, Li T, Wang Y, Kong Z, Zheng Q, Zhang J, Yu H, Gu Y, Xia N, Li S. Wang K, et al. Among authors: li s, li t, li y, li j, li q. Microb Cell Fact. 2021 Dec 20;20(1):227. doi: 10.1186/s12934-021-01719-8. Microb Cell Fact. 2021. PMID: 34930257 Free PMC article.
SARS-CoV-2 spike produced in insect cells elicits high neutralization titres in non-human primates.
Li T, Zheng Q, Yu H, Wu D, Xue W, Xiong H, Huang X, Nie M, Yue M, Rong R, Zhang S, Zhang Y, Wu Y, Wang S, Zha Z, Chen T, Deng T, Wang Y, Zhang T, Chen Y, Yuan Q, Zhao Q, Zhang J, Gu Y, Li S, Xia N. Li T, et al. Among authors: li s. Emerg Microbes Infect. 2020 Dec;9(1):2076-2090. doi: 10.1080/22221751.2020.1821583. Emerg Microbes Infect. 2020. PMID: 32897177 Free PMC article.
A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice.
Liu L, Chen T, Zhou L, Sun J, Li Y, Nie M, Xiong H, Zhu Y, Xue W, Wu Y, Li T, Zhang T, Kong Z, Yu H, Zhang J, Gu Y, Zheng Q, Zhao Q, Xia N, Li S. Liu L, et al. Among authors: li s, li t, li y. Front Microbiol. 2022 Apr 26;13:854630. doi: 10.3389/fmicb.2022.854630. eCollection 2022. Front Microbiol. 2022. PMID: 35558112 Free PMC article.
Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding.
He M, Chi X, Zha Z, Li Y, Chen J, Huang Y, Huang S, Yu M, Wang Z, Song S, Liu X, Wei S, Li Z, Li T, Wang Y, Yu H, Zhao Q, Zhang J, Zheng Q, Gu Y, Li S, Xia N. He M, et al. Among authors: li s, li t, li y, li z. J Virol. 2021 Mar 10;95(7):e01587-20. doi: 10.1128/JVI.01587-20. Epub 2021 Jan 20. J Virol. 2021. PMID: 33472937 Free PMC article.
A stepwise docking molecular dynamics approach for simulating antibody recognition with substantial conformational changes.
Huang Y, Li Z, Hong Q, Zhou L, Ma Y, Hu Y, Xin J, Li T, Kong Z, Zheng Q, Chen Y, Zhao Q, Gu Y, Zhang J, Wang Y, Yu H, Li S, Xia N. Huang Y, et al. Among authors: li s, li t, li z. Comput Struct Biotechnol J. 2022 Jan 18;20:710-720. doi: 10.1016/j.csbj.2022.01.012. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35198128 Free PMC article.
Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.
Wang S, Sun H, Zhang Y, Yuan L, Wang Y, Zhang T, Wang S, Zhang J, Yu H, Xiong H, Tang Z, Liu L, Huang Y, Chen X, Li T, Ying D, Liu C, Chen Z, Yuan Q, Zhang J, Cheng T, Li S, Guan Y, Zheng Q, Zheng Z, Xia N. Wang S, et al. Among authors: li s, li t. Cell Rep. 2022 May 24;39(8):110862. doi: 10.1016/j.celrep.2022.110862. Epub 2022 May 8. Cell Rep. 2022. PMID: 35594869 Free PMC article.
The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2.
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N. Xiong H, et al. Among authors: li s, li t. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2204256119. doi: 10.1073/pnas.2204256119. Epub 2022 Aug 16. Proc Natl Acad Sci U S A. 2022. PMID: 35972965 Free PMC article.
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