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Page 1
Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts.
Andersen MK, Skotte L, Jørsboe E, Polito R, Stæger FF, Aldiss P, Hanghøj K, Waples RK, Santander CG, Grarup N, Dahl-Petersen IK, Diaz LJ, Overvad M, Senftleber NK, Søborg B, Larsen CVL, Lemoine C, Pedersen O, Feenstra B, Bjerregaard P, Melbye M, Jørgensen ME, Færgeman NJ, Koch A, Moritz T, Gillum MP, Moltke I, Hansen T, Albrechtsen A. Andersen MK, et al. Among authors: staeger ff. Gastroenterology. 2022 Apr;162(4):1171-1182.e3. doi: 10.1053/j.gastro.2021.12.236. Epub 2021 Dec 13. Gastroenterology. 2022. PMID: 34914943 Free article.
Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles.
Lilius TO, Mortensen KN, Deville C, Lohela TJ, Stæger FF, Sigurdsson B, Fiordaliso EM, Rosenholm M, Kamphuis C, Beekman FJ, Jensen AI, Nedergaard M. Lilius TO, et al. Among authors: staeger ff. J Control Release. 2023 Mar;355:135-148. doi: 10.1016/j.jconrel.2023.01.054. Epub 2023 Feb 4. J Control Release. 2023. PMID: 36731802 Free article.
High genetic diversity and low differentiation reflect the ecological versatility of the African leopard.
Pečnerová P, Garcia-Erill G, Liu X, Nursyifa C, Waples RK, Santander CG, Quinn L, Frandsen P, Meisner J, Stæger FF, Rasmussen MS, Brüniche-Olsen A, Hviid Friis Jørgensen C, da Fonseca RR, Siegismund HR, Albrechtsen A, Heller R, Moltke I, Hanghøj K. Pečnerová P, et al. Among authors: staeger ff. Curr Biol. 2021 May 10;31(9):1862-1871.e5. doi: 10.1016/j.cub.2021.01.064. Epub 2021 Feb 25. Curr Biol. 2021. PMID: 33636121 Free article.
Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic.
Duncan CJA, Skouboe MK, Howarth S, Hollensen AK, Chen R, Børresen ML, Thompson BJ, Stremenova Spegarova J, Hatton CF, Stæger FF, Andersen MK, Whittaker J, Paludan SR, Jørgensen SE, Thomsen MK, Mikkelsen JG, Heilmann C, Buhas D, Øbro NF, Bay JT, Marquart HV, de la Morena MT, Klejka JA, Hirschfeld M, Borgwardt L, Forss I, Masmas T, Poulsen A, Noya F, Rouleau G, Hansen T, Zhou S, Albrechtsen A, Alizadehfar R, Allenspach EJ, Hambleton S, Mogensen TH. Duncan CJA, et al. Among authors: staeger ff. J Exp Med. 2022 Jun 6;219(6):e20212427. doi: 10.1084/jem.20212427. Epub 2022 Apr 20. J Exp Med. 2022. PMID: 35442417 Free PMC article.
An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention.
Jørsboe E, Andersen MK, Skotte L, Stæger FF, Færgeman NJ, Hanghøj K, Santander CG, Senftleber NK, Diaz LJ, Overvad M, Waples RK, Geller F, Bjerregaard P, Melbye M, Larsen CVL, Feenstra B, Anders Koch, Jørgensen ME, Grarup N, Moltke I, Albrechtsen A, Hansen T. Jørsboe E, et al. Among authors: staeger ff. HGG Adv. 2022 Jun 9;3(4):100118. doi: 10.1016/j.xhgg.2022.100118. eCollection 2022 Oct 13. HGG Adv. 2022. PMID: 36267056 Free PMC article.
A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland.
Thuesen ACB, Stæger FF, Kaci A, Solheim MH, Aukrust I, Jørsboe E, Santander CG, Andersen MK, Li Z, Gilly A, Stinson SE, Gjesing AP, Bjerregaard P, Pedersen ML, Larsen CVL, Grarup N, Jørgensen ME, Zeggini E, Bjørkhaug L, Njølstad PR, Albrechtsen A, Moltke I, Hansen T. Thuesen ACB, et al. Among authors: staeger ff. Lancet Reg Health Eur. 2022 Nov 11;24:100529. doi: 10.1016/j.lanepe.2022.100529. eCollection 2023 Jan. Lancet Reg Health Eur. 2022. PMID: 36649380 Free PMC article.
GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal.
Senftleber NK, Andersen MK, Jørsboe E, Stæger FF, Nøhr AK, Garcia-Erill G, Meisner J, Santander CG, Balboa RF, Gilly A, Bjerregaard P, Larsen CVL, Grarup N, Jørgensen ME, Zeggini E, Moltke I, Hansen T, Albrechtsen A. Senftleber NK, et al. Among authors: staeger ff. Eur J Hum Genet. 2024 Feb;32(2):215-223. doi: 10.1038/s41431-023-01485-8. Epub 2023 Oct 30. Eur J Hum Genet. 2024. PMID: 37903942 Free PMC article.
18 results