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Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts.
Andersen MK, Skotte L, Jørsboe E, Polito R, Stæger FF, Aldiss P, Hanghøj K, Waples RK, Santander CG, Grarup N, Dahl-Petersen IK, Diaz LJ, Overvad M, Senftleber NK, Søborg B, Larsen CVL, Lemoine C, Pedersen O, Feenstra B, Bjerregaard P, Melbye M, Jørgensen ME, Færgeman NJ, Koch A, Moritz T, Gillum MP, Moltke I, Hansen T, Albrechtsen A. Andersen MK, et al. Among authors: faergeman nj. Gastroenterology. 2022 Apr;162(4):1171-1182.e3. doi: 10.1053/j.gastro.2021.12.236. Epub 2021 Dec 13. Gastroenterology. 2022. PMID: 34914943 Free article.
Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis.
Sustarsic EG, Ma T, Lynes MD, Larsen M, Karavaeva I, Havelund JF, Nielsen CH, Jedrychowski MP, Moreno-Torres M, Lundh M, Plucinska K, Jespersen NZ, Grevengoed TJ, Kramar B, Peics J, Hansen JB, Shamsi F, Forss I, Neess D, Keipert S, Wang J, Stohlmann K, Brandslund I, Christensen C, Jørgensen ME, Linneberg A, Pedersen O, Kiebish MA, Qvortrup K, Han X, Pedersen BK, Jastroch M, Mandrup S, Kjær A, Gygi SP, Hansen T, Gillum MP, Grarup N, Emanuelli B, Nielsen S, Scheele C, Tseng YH, Færgeman NJ, Gerhart-Hines Z. Sustarsic EG, et al. Among authors: faergeman nj. Cell Metab. 2018 Jul 3;28(1):159-174.e11. doi: 10.1016/j.cmet.2018.05.003. Epub 2018 May 31. Cell Metab. 2018. PMID: 29861389 Free PMC article.
A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults.
Hansen LBS, Roager HM, Søndertoft NB, Gøbel RJ, Kristensen M, Vallès-Colomer M, Vieira-Silva S, Ibrügger S, Lind MV, Mærkedahl RB, Bahl MI, Madsen ML, Havelund J, Falony G, Tetens I, Nielsen T, Allin KH, Frandsen HL, Hartmann B, Holst JJ, Sparholt MH, Holck J, Blennow A, Moll JM, Meyer AS, Hoppe C, Poulsen JH, Carvalho V, Sagnelli D, Dalgaard MD, Christensen AF, Lydolph MC, Ross AB, Villas-Bôas S, Brix S, Sicheritz-Pontén T, Buschard K, Linneberg A, Rumessen JJ, Ekstrøm CT, Ritz C, Kristiansen K, Nielsen HB, Vestergaard H, Færgeman NJ, Raes J, Frøkiær H, Hansen T, Lauritzen L, Gupta R, Licht TR, Pedersen O. Hansen LBS, et al. Among authors: faergeman nj. Nat Commun. 2018 Nov 13;9(1):4630. doi: 10.1038/s41467-018-07019-x. Nat Commun. 2018. PMID: 30425247 Free PMC article. Clinical Trial.
An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention.
Jørsboe E, Andersen MK, Skotte L, Stæger FF, Færgeman NJ, Hanghøj K, Santander CG, Senftleber NK, Diaz LJ, Overvad M, Waples RK, Geller F, Bjerregaard P, Melbye M, Larsen CVL, Feenstra B, Anders Koch, Jørgensen ME, Grarup N, Moltke I, Albrechtsen A, Hansen T. Jørsboe E, et al. Among authors: faergeman nj. HGG Adv. 2022 Jun 9;3(4):100118. doi: 10.1016/j.xhgg.2022.100118. eCollection 2022 Oct 13. HGG Adv. 2022. PMID: 36267056 Free PMC article.
Epidermal Acyl-CoA-binding protein is indispensable for systemic energy homeostasis.
Neess D, Kruse V, Marcher AB, Wæde MR, Vistisen J, Møller PM, Petersen R, Brewer JR, Ma T, Colleluori G, Severi I, Cinti S, Gerhart-Hines Z, Mandrup S, Færgeman NJ. Neess D, et al. Among authors: faergeman nj. Mol Metab. 2021 Feb;44:101144. doi: 10.1016/j.molmet.2020.101144. Epub 2020 Dec 18. Mol Metab. 2021. PMID: 33346070 Free PMC article.
128 results