Li J - Search Results

1

Discovery of spiro amide SHR902275: A potent, selective, and efficacious RAF inhibitor targeting RAS mutant cancers.

Zhao P, Zhuang L, Wang X, Huang S, Wu H, Zhou Y, Yan Y, Zhang F, Shen R, Li J, Liu S, Zhang R, Dong P, Mao Y, Fan Y, He C, Sun J, Zhang L, Hu Q, Wan H, Feng J, Bai C, He F, Tao W. Zhao P, et al. Among authors: li j. Eur J Med Chem. 2022 Jan 15;228:114040. doi: 10.1016/j.ejmech.2021.114040. Epub 2021 Dec 7. Eur J Med Chem. 2022. PMID: 34906761

2

Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α1A-Adrenoceptor Antagonists.

Zhao F, Li J, Chen Y, Tian Y, Wu C, Xie Y, Zhou Y, Wang J, Xie X, Liu H. Zhao F, et al. Among authors: li j. J Med Chem. 2016 Apr 28;59(8):3826-39. doi: 10.1021/acs.jmedchem.5b02023. Epub 2016 Apr 13. J Med Chem. 2016. PMID: 27031406

3

Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective α_1A-Adrenoceptor Antagonists.

Guo D, Li J, Lin H, Zhou Y, Chen Y, Zhao F, Sun H, Zhang D, Li H, Shoichet BK, Shan L, Zhang W, Xie X, Jiang H, Liu H. Guo D, et al. Among authors: li j, li h. J Med Chem. 2016 Oct 27;59(20):9489-9502. doi: 10.1021/acs.jmedchem.6b01217. Epub 2016 Oct 12. J Med Chem. 2016. PMID: 27709945

4

Design and synthesis of neolamellarin a derivatives targeting heat shock protein 90.

Jiang L, Yin R, Wang X, Dai J, Li J, Jiang T, Yu R. Jiang L, et al. Among authors: li j. Eur J Med Chem. 2017 Jul 28;135:24-33. doi: 10.1016/j.ejmech.2017.04.019. Epub 2017 Apr 15. Eur J Med Chem. 2017. PMID: 28426997

5

Synthesis and bioevaluation of 1-phenyl-pyrazole-4-carboxylic acid derivatives as potent xanthine oxidoreductase inhibitors.

Li J, Wu F, Liu X, Zou Y, Chen H, Li Z, Zhang L. Li J, et al. Among authors: li z. Eur J Med Chem. 2017 Nov 10;140:20-30. doi: 10.1016/j.ejmech.2017.08.047. Epub 2017 Aug 24. Eur J Med Chem. 2017. PMID: 28918097

6

Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position.

Yang CR, Peng B, Cao SL, Ren TT, Jiang W, Wang FC, Li YS, Wang G, Li Z, Xu S, Liao J, Wang H, Li J, Xu X. Yang CR, et al. Among authors: li z, li j, li ys. Eur J Med Chem. 2018 Jun 25;154:324-340. doi: 10.1016/j.ejmech.2018.05.028. Epub 2018 May 21. Eur J Med Chem. 2018. PMID: 29843103

7

Synthesis and biological evaluation of quinazolin-4(3H)-one derivatives bearing dithiocarbamate side chain at C2-position as potential antitumor agents.

Ding PP, Gao M, Mao BB, Cao SL, Liu CH, Yang CR, Li ZF, Liao J, Zhao H, Li Z, Li J, Wang H, Xu X. Ding PP, et al. Among authors: li z, li j, li zf. Eur J Med Chem. 2016 Jan 27;108:364-373. doi: 10.1016/j.ejmech.2015.11.044. Epub 2015 Nov 28. Eur J Med Chem. 2016. PMID: 26703795

8

Synthesis, crystal structures and antitumor activity of two platinum(II) complexes with methyl hydrazinecarbodithioate derivatives of indolin-2-one.

Li YS, Peng B, Ma L, Cao SL, Bai LL, Yang CR, Wan CQ, Yan HJ, Ding PP, Li ZF, Liao J, Meng YY, Wang HL, Li J, Xu X. Li YS, et al. Among authors: li j, li zf. Eur J Med Chem. 2017 Feb 15;127:137-146. doi: 10.1016/j.ejmech.2016.12.050. Epub 2016 Dec 26. Eur J Med Chem. 2017. PMID: 28039772

9

Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis.

Shi Y, Duan YH, Ji YY, Wang ZL, Wu YR, Gunosewoyo H, Xie XY, Chen JZ, Yang F, Li J, Tang J, Xie X, Yu LF. Shi Y, et al. Among authors: li j. J Med Chem. 2017 Aug 24;60(16):7067-7083. doi: 10.1021/acs.jmedchem.7b00724. Epub 2017 Aug 3. J Med Chem. 2017. PMID: 28726401

10

Structure-based discovery of cytotoxic dimeric tetrahydroxanthones as potential topoisomerase I inhibitors from a marine-derived fungus.

Wu G, Qi X, Mo X, Yu G, Wang Q, Zhu T, Gu Q, Liu M, Li J, Li D. Wu G, et al. Among authors: li d, li j. Eur J Med Chem. 2018 Mar 25;148:268-278. doi: 10.1016/j.ejmech.2018.02.041. Epub 2018 Feb 13. Eur J Med Chem. 2018. PMID: 29466776

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