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Page 1
The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis.
Kobayashi H, Gieniec KA, Lannagan TRM, Wang T, Asai N, Mizutani Y, Iida T, Ando R, Thomas EM, Sakai A, Suzuki N, Ichinose M, Wright JA, Vrbanac L, Ng JQ, Goyne J, Radford G, Lawrence MJ, Sammour T, Hayakawa Y, Klebe S, Shin AE, Asfaha S, Bettington ML, Rieder F, Arpaia N, Danino T, Butler LM, Burt AD, Leedham SJ, Rustgi AK, Mukherjee S, Takahashi M, Wang TC, Enomoto A, Woods SL, Worthley DL. Kobayashi H, et al. Among authors: vrbanac l. Gastroenterology. 2022 Mar;162(3):890-906. doi: 10.1053/j.gastro.2021.11.037. Epub 2021 Dec 6. Gastroenterology. 2022. PMID: 34883119 Free PMC article.
Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.
Lannagan TRM, Lee YK, Wang T, Roper J, Bettington ML, Fennell L, Vrbanac L, Jonavicius L, Somashekar R, Gieniec K, Yang M, Ng JQ, Suzuki N, Ichinose M, Wright JA, Kobayashi H, Putoczki TL, Hayakawa Y, Leedham SJ, Abud HE, Yilmaz ÖH, Marker J, Klebe S, Wirapati P, Mukherjee S, Tejpar S, Leggett BA, Whitehall VLJ, Worthley DL, Woods SL. Lannagan TRM, et al. Among authors: vrbanac l. Gut. 2019 Apr;68(4):684-692. doi: 10.1136/gutjnl-2017-315920. Epub 2018 Apr 17. Gut. 2019. PMID: 29666172 Free PMC article.
Medium-throughput Drug Screening of Patient-derived Organoids from Colorectal Peritoneal Metastases to Direct Personalized Therapy.
Narasimhan V, Wright JA, Churchill M, Wang T, Rosati R, Lannagan TRM, Vrbanac L, Richardson AB, Kobayashi H, Price T, Tye GXY, Marker J, Hewett PJ, Flood MP, Pereira S, Whitney GA, Michael M, Tie J, Mukherjee S, Grandori C, Heriot AG, Worthley DL, Ramsay RG, Woods SL. Narasimhan V, et al. Among authors: vrbanac l. Clin Cancer Res. 2020 Jul 15;26(14):3662-3670. doi: 10.1158/1078-0432.CCR-20-0073. Epub 2020 May 6. Clin Cancer Res. 2020. PMID: 32376656 Free PMC article.
The Balance of Stromal BMP Signaling Mediated by GREM1 and ISLR Drives Colorectal Carcinogenesis.
Kobayashi H, Gieniec KA, Wright JA, Wang T, Asai N, Mizutani Y, Lida T, Ando R, Suzuki N, Lannagan TRM, Ng JQ, Hara A, Shiraki Y, Mii S, Ichinose M, Vrbanac L, Lawrence MJ, Sammour T, Uehara K, Davies G, Lisowski L, Alexander IE, Hayakawa Y, Butler LM, Zannettino ACW, Din MO, Hasty J, Burt AD, Leedham SJ, Rustgi AK, Mukherjee S, Wang TC, Enomoto A, Takahashi M, Worthley DL, Woods SL. Kobayashi H, et al. Among authors: vrbanac l. Gastroenterology. 2021 Mar;160(4):1224-1239.e30. doi: 10.1053/j.gastro.2020.11.011. Epub 2020 Nov 14. Gastroenterology. 2021. PMID: 33197448
Stromal DLK1 promotes proliferation and inhibits differentiation of the intestinal epithelium during development.
Ichinose M, Suzuki N, Wang T, Wright JA, Lannagan TRM, Vrbanac L, Kobayashi H, Gieniec KA, Ng JQ, Hayakawa Y, García-Gallastegui P, Monsalve EM, Bauer SR, Laborda J, García-Ramírez JJ, Ibarretxe G, Worthley DL, Woods SL. Ichinose M, et al. Among authors: vrbanac l. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 1;320(4):G506-G520. doi: 10.1152/ajpgi.00445.2020. Epub 2021 Jan 20. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33470182 Free article.
The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses.
Ichinose M, Suzuki N, Wang T, Kobayashi H, Vrbanac L, Ng JQ, Wright JA, Lannagan TRM, Gieniec KA, Lewis M, Ando R, Enomoto A, Koblar S, Thomas P, Worthley DL, Woods SL. Ichinose M, et al. Among authors: vrbanac l. Development. 2021 Jul 15;148(14):dev195883. doi: 10.1242/dev.195883. Epub 2021 Jul 12. Development. 2021. PMID: 34184027 Free PMC article.
The Antianginal Drug Perhexiline Displays Cytotoxicity against Colorectal Cancer Cells In Vitro: A Potential for Drug Repurposing.
Dhakal B, Li CMY, Li R, Yeo K, Wright JA, Gieniec KA, Vrbanac L, Sammour T, Lawrence M, Thomas M, Lewis M, Perry J, Worthley DL, Woods SL, Drew P, Sallustio BC, Smith E, Horowitz JD, Maddern GJ, Licari G, Fenix K. Dhakal B, et al. Among authors: vrbanac l. Cancers (Basel). 2022 Feb 18;14(4):1043. doi: 10.3390/cancers14041043. Cancers (Basel). 2022. PMID: 35205791 Free PMC article.
Loss of Grem1-articular cartilage progenitor cells causes osteoarthritis.
Ng JQ, Jafarov TH, Little CB, Wang T, Ali A, Ma Y, Radford GA, Vrbanac L, Ichinose M, Whittle S, Hunter D, Lannagan TR, Suzuki N, Goyne JM, Kobayashi H, Wang TC, Haynes D, Menicanin D, Gronthos S, Worthley DL, Woods SL, Mukherjee S. Ng JQ, et al. Among authors: vrbanac l. bioRxiv [Preprint]. 2023 Mar 30:2023.03.29.534651. doi: 10.1101/2023.03.29.534651. bioRxiv. 2023. PMID: 37034712 Free PMC article. Preprint.
17 results