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A population study using the human erythrocyte PIG-A assay.
Cao Y, Yang L, Feng N, Shi O, Xi J, You X, Yin C, Yang H, Horibata K, Honma M, Qian B, Weng W, Luan Y. Cao Y, et al. Among authors: luan y. Environ Mol Mutagen. 2016 Oct;57(8):605-614. doi: 10.1002/em.22040. Epub 2016 Sep 1. Environ Mol Mutagen. 2016. PMID: 27581231
Detoxification of benzo[a]pyrene primarily depends on cytochrome P450, while bioactivation involves additional oxidoreductases including 5-lipoxygenase, cyclooxygenase, and aldo-keto reductase in the liver.
Wang L, Xu W, Ma L, Zhang S, Zhang K, Ye P, Xing G, Zhang X, Cao Y, Xi J, Gu J, Luan Y. Wang L, et al. Among authors: luan y. J Biochem Mol Toxicol. 2017 Jul;31(7). doi: 10.1002/jbt.21902. Epub 2017 Jan 23. J Biochem Mol Toxicol. 2017. PMID: 28111842
1,439 results