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Nitroxoline and its derivatives are potent inhibitors of metallo-β-lactamases.
Proschak A, Martinelli G, Frank D, Rotter MJ, Brunst S, Weizel L, Burgers LD, Fürst R, Proschak E, Sosič I, Gobec S, Wichelhaus TA. Proschak A, et al. Among authors: wichelhaus ta. Eur J Med Chem. 2022 Jan 15;228:113975. doi: 10.1016/j.ejmech.2021.113975. Epub 2021 Nov 13. Eur J Med Chem. 2022. PMID: 34865870
Correction to Approved Drugs Containing Thiols as Inhibitors of Metallo-β-lactamases: Strategy To Combat Multidrug-Resistant Bacteria.
Klingler FM, Wichelhaus TA, Frank D, Cuesta-Bernal J, El-Delik J, Müller HF, Sjuts H, Göttig S, Koenigs A, Pos KM, Pogoryelov D, Proschak E. Klingler FM, et al. Among authors: wichelhaus ta. J Med Chem. 2015 Aug 13;58(15):6320. doi: 10.1021/acs.jmedchem.5b01097. Epub 2015 Jul 30. J Med Chem. 2015. PMID: 26225625 No abstract available.
Promoter Activation in Δhfq Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing.
Bode E, Heinrich AK, Hirschmann M, Abebew D, Shi YN, Vo TD, Wesche F, Shi YM, Grün P, Simonyi S, Keller N, Engel Y, Wenski S, Bennet R, Beyer S, Bischoff I, Buaya A, Brandt S, Cakmak I, Çimen H, Eckstein S, Frank D, Fürst R, Gand M, Geisslinger G, Hazir S, Henke M, Heermann R, Lecaudey V, Schäfer W, Schiffmann S, Schüffler A, Schwenk R, Skaljac M, Thines E, Thines M, Ulshöfer T, Vilcinskas A, Wichelhaus TA, Bode HB. Bode E, et al. Among authors: wichelhaus ta. Angew Chem Int Ed Engl. 2019 Dec 19;58(52):18957-18963. doi: 10.1002/anie.201910563. Epub 2019 Dec 12. Angew Chem Int Ed Engl. 2019. PMID: 31693786 Free PMC article.
147 results