Gobec S - Search Results

1

Nitroxoline and its derivatives are potent inhibitors of metallo-β-lactamases.

Proschak A, Martinelli G, Frank D, Rotter MJ, Brunst S, Weizel L, Burgers LD, Fürst R, Proschak E, Sosič I, Gobec S, Wichelhaus TA. Proschak A, et al. Among authors: gobec s. Eur J Med Chem. 2022 Jan 15;228:113975. doi: 10.1016/j.ejmech.2021.113975. Epub 2021 Nov 13. Eur J Med Chem. 2022. PMID: 34865870

2

Cinnamic acid esters as potent inhibitors of fungal 17beta-hydroxysteroid dehydrogenase--a model enzyme of the short-chain dehydrogenase/reductase superfamily.

Gobec S, Sova M, Kristan K, Rizner TL. Gobec S, et al. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3933-6. doi: 10.1016/j.bmcl.2004.05.069. Bioorg Med Chem Lett. 2004. PMID: 15225701

3

Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD.

Strancar K, Blanot D, Gobec S. Strancar K, et al. Among authors: gobec s. Bioorg Med Chem Lett. 2006 Jan 15;16(2):343-8. doi: 10.1016/j.bmcl.2005.09.086. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16271472

4

Flavonoids and cinnamic acid esters as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase: a synthesis, QSAR and modelling study.

Sova M, Perdih A, Kotnik M, Kristan K, Rizner TL, Solmajer T, Gobec S. Sova M, et al. Among authors: gobec s. Bioorg Med Chem. 2006 Nov 15;14(22):7404-18. doi: 10.1016/j.bmc.2006.07.027. Epub 2006 Aug 7. Bioorg Med Chem. 2006. PMID: 16891119

5

Inhibitors of cathepsin B.

Frlan R, Gobec S. Frlan R, et al. Among authors: gobec s. Curr Med Chem. 2006;13(19):2309-27. doi: 10.2174/092986706777935122. Curr Med Chem. 2006. PMID: 16918357 Review.

6

Design, synthesis, biochemical evaluation and antimycobacterial action of phosphonate inhibitors of antigen 85C, a crucial enzyme involved in biosynthesis of the mycobacterial cell wall.

Gobec S, Plantan I, Mravljak J, Svajger U, Wilson RA, Besra GS, Soares SL, Appelberg R, Kikelj D. Gobec S, et al. Eur J Med Chem. 2007 Jan;42(1):54-63. doi: 10.1016/j.ejmech.2006.08.007. Epub 2006 Sep 28. Eur J Med Chem. 2007. PMID: 17010479

7

Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme.

Humljan J, Kotnik M, Contreras-Martel C, Blanot D, Urleb U, Dessen A, Solmajer T, Gobec S. Humljan J, et al. Among authors: gobec s. J Med Chem. 2008 Dec 11;51(23):7486-94. doi: 10.1021/jm800762u. J Med Chem. 2008. PMID: 19007109

8

Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase.

Tomasić T, Zidar N, Rupnik V, Kovac A, Blanot D, Gobec S, Kikelj D, Masic LP. Tomasić T, et al. Among authors: gobec s. Bioorg Med Chem Lett. 2009 Jan 1;19(1):153-7. doi: 10.1016/j.bmcl.2008.10.129. Epub 2008 Nov 5. Bioorg Med Chem Lett. 2009. PMID: 19014883

9

Discovery of new inhibitors of D-alanine:D-alanine ligase by structure-based virtual screening.

Kovac A, Konc J, Vehar B, Bostock JM, Chopra I, Janezic D, Gobec S. Kovac A, et al. Among authors: gobec s. J Med Chem. 2008 Dec 11;51(23):7442-8. doi: 10.1021/jm800726b. J Med Chem. 2008. PMID: 19053785

10

New cyclopentane derivatives as inhibitors of steroid metabolizing enzymes AKR1C1 and AKR1C3.

Stefane B, Brozic P, Vehovc M, Rizner TL, Gobec S. Stefane B, et al. Among authors: gobec s. Eur J Med Chem. 2009 Jun;44(6):2563-71. doi: 10.1016/j.ejmech.2009.01.028. Epub 2009 Feb 5. Eur J Med Chem. 2009. PMID: 19237229

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