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Page 1
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53.
Nowak RP, Tumber A, Hendrix E, Ansari MSZ, Sabatino M, Antonini L, Andrijes R, Salah E, Mautone N, Pellegrini FR, Simelis K, Kawamura A, Johansson C, Passeri D, Pellicciari R, Ciogli A, Del Bufalo D, Ragno R, Coleman ML, Trisciuoglio D, Mai A, Oppermann U, Schofield CJ, Rotili D. Nowak RP, et al. Among authors: mautone n. J Med Chem. 2021 Dec 9;64(23):17031-17050. doi: 10.1021/acs.jmedchem.1c00605. Epub 2021 Nov 29. J Med Chem. 2021. PMID: 34843649 Free PMC article.
From PARP1 to TNKS2 Inhibition: A Structure-Based Approach.
Tomassi S, Pfahler J, Mautone N, Rovere A, Esposito C, Passeri D, Pellicciari R, Novellino E, Pannek M, Steegborn C, Paiardini A, Mai A, Rotili D. Tomassi S, et al. Among authors: mautone n. ACS Med Chem Lett. 2020 Feb 3;11(5):862-868. doi: 10.1021/acsmedchemlett.9b00654. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435397 Free PMC article.
Sirtuin modulators: past, present, and future perspectives.
Fiorentino F, Mautone N, Menna M, D'Acunzo F, Mai A, Rotili D. Fiorentino F, et al. Among authors: mautone n. Future Med Chem. 2022 Jun;14(12):915-939. doi: 10.4155/fmc-2022-0031. Epub 2022 May 18. Future Med Chem. 2022. PMID: 35583203 Free PMC article. Review.
Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes.
Matutino Bastos T, Botelho Pereira Soares M, Haddad Franco C, Alcântara L, Antonini L, Sabatino M, Mautone N, Holanda Freitas-Junior L, Moraes CB, Ragno R, Rotili D, Schenkman S, Mai A, Silvio Moretti N. Matutino Bastos T, et al. Among authors: mautone n. Int J Mol Sci. 2020 May 22;21(10):3659. doi: 10.3390/ijms21103659. Int J Mol Sci. 2020. PMID: 32455951 Free PMC article.
Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation.
Fioravanti R, Romanelli A, Mautone N, Di Bello E, Rovere A, Corinti D, Zwergel C, Valente S, Rotili D, Botrugno OA, Dessanti P, Vultaggio S, Vianello P, Cappa A, Binda C, Mattevi A, Minucci S, Mercurio C, Varasi M, Mai A. Fioravanti R, et al. Among authors: mautone n. ChemMedChem. 2020 Apr 3;15(7):643-658. doi: 10.1002/cmdc.201900730. Epub 2020 Feb 14. ChemMedChem. 2020. PMID: 32003940 Free PMC article.