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Bioengineering commensal bacteria-derived outer membrane vesicles for delivery of biologics to the gastrointestinal and respiratory tract.
Carvalho AL, Fonseca S, Miquel-Clopés A, Cross K, Kok KS, Wegmann U, Gil-Cordoso K, Bentley EG, Al Katy SHM, Coombes JL, Kipar A, Stentz R, Stewart JP, Carding SR. Carvalho AL, et al. Among authors: fonseca s. J Extracell Vesicles. 2019 Jun 24;8(1):1632100. doi: 10.1080/20013078.2019.1632100. eCollection 2019. J Extracell Vesicles. 2019. PMID: 31275534 Free PMC article.
Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell-type specific manner that are altered in inflammatory bowel disease.
Gul L, Modos D, Fonseca S, Madgwick M, Thomas JP, Sudhakar P, Booth C, Stentz R, Carding SR, Korcsmaros T. Gul L, et al. Among authors: fonseca s. J Extracell Vesicles. 2022 Jan;11(1):e12189. doi: 10.1002/jev2.12189. J Extracell Vesicles. 2022. PMID: 35064769 Free PMC article.
767 results