Walensky LD - Search Results

1

Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets.

Fu A, van Rooyen L, Evans L, Armstrong N, Avizonis D, Kin T, Bird GH, Reddy A, Chouchani ET, Liesa-Roig M, Walensky LD, Shapiro AMJ, Danial NN. Fu A, et al. Among authors: walensky ld. Cell Rep. 2021 Nov 23;37(8):110037. doi: 10.1016/j.celrep.2021.110037. Cell Rep. 2021. PMID: 34818536 Free PMC article.

2

Dual role of proapoptotic BAD in insulin secretion and beta cell survival.

Danial NN, Walensky LD, Zhang CY, Choi CS, Fisher JK, Molina AJ, Datta SR, Pitter KL, Bird GH, Wikstrom JD, Deeney JT, Robertson K, Morash J, Kulkarni A, Neschen S, Kim S, Greenberg ME, Corkey BE, Shirihai OS, Shulman GI, Lowell BB, Korsmeyer SJ. Danial NN, et al. Among authors: walensky ld. Nat Med. 2008 Feb;14(2):144-53. doi: 10.1038/nm1717. Epub 2008 Jan 27. Nat Med. 2008. PMID: 18223655 Free PMC article.

3

Synthesis and biophysical characterization of stabilized alpha-helices of BCL-2 domains.

Bird GH, Bernal F, Pitter K, Walensky LD. Bird GH, et al. Among authors: walensky ld. Methods Enzymol. 2008;446:369-86. doi: 10.1016/S0076-6879(08)01622-4. Methods Enzymol. 2008. PMID: 18603134 Free PMC article.

4

BAX activation is initiated at a novel interaction site.

Gavathiotis E, Suzuki M, Davis ML, Pitter K, Bird GH, Katz SG, Tu HC, Kim H, Cheng EH, Tjandra N, Walensky LD. Gavathiotis E, et al. Among authors: walensky ld. Nature. 2008 Oct 23;455(7216):1076-81. doi: 10.1038/nature07396. Nature. 2008. PMID: 18948948 Free PMC article.

5

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic.

Bird GH, Madani N, Perry AF, Princiotto AM, Supko JG, He X, Gavathiotis E, Sodroski JG, Walensky LD. Bird GH, et al. Among authors: walensky ld. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14093-8. doi: 10.1073/pnas.1002713107. Epub 2010 Jul 21. Proc Natl Acad Sci U S A. 2010. PMID: 20660316 Free PMC article.

6

BH3-triggered structural reorganization drives the activation of proapoptotic BAX.

Gavathiotis E, Reyna DE, Davis ML, Bird GH, Walensky LD. Gavathiotis E, et al. Among authors: walensky ld. Mol Cell. 2010 Nov 12;40(3):481-92. doi: 10.1016/j.molcel.2010.10.019. Mol Cell. 2010. PMID: 21070973 Free PMC article.

7

Photoreactive stapled BH3 peptides to dissect the BCL-2 family interactome.

Braun CR, Mintseris J, Gavathiotis E, Bird GH, Gygi SP, Walensky LD. Braun CR, et al. Among authors: walensky ld. Chem Biol. 2010 Dec 22;17(12):1325-33. doi: 10.1016/j.chembiol.2010.09.015. Chem Biol. 2010. PMID: 21168768 Free PMC article.

8

Characterization of a core fragment of the rhesus monkey TRIM5α protein.

Kar AK, Mao Y, Bird G, Walensky L, Sodroski J. Kar AK, et al. BMC Biochem. 2011 Jan 4;12:1. doi: 10.1186/1471-2091-12-1. BMC Biochem. 2011. PMID: 21205312 Free PMC article.

9

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.

LaBelle JL, Katz SG, Bird GH, Gavathiotis E, Stewart ML, Lawrence C, Fisher JK, Godes M, Pitter K, Kung AL, Walensky LD. LaBelle JL, et al. Among authors: walensky ld. J Clin Invest. 2012 Jun;122(6):2018-31. doi: 10.1172/JCI46231. Epub 2012 May 24. J Clin Invest. 2012. PMID: 22622039 Free PMC article.

10

Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling.

Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulciniti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, Walensky LD, Carrasco DR. Takada K, et al. Among authors: walensky ld. Sci Transl Med. 2012 Aug 22;4(148):148ra117. doi: 10.1126/scitranslmed.3003808. Sci Transl Med. 2012. PMID: 22914623 Free PMC article.

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