Green KN - Search Results

1

Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice.

Olivarria GM, Cheng Y, Furman S, Pachow C, Hohsfield LA, Smith-Geater C, Miramontes R, Wu J, Burns MS, Tsourmas KI, Stocksdale J, Manlapaz C, Yong WH, Teijaro J, Edwards R, Green KN, Thompson LM, Lane TE. Olivarria GM, et al. Among authors: green kn. bioRxiv [Preprint]. 2021 Nov 17:2021.11.15.468761. doi: 10.1101/2021.11.15.468761. bioRxiv. 2021. Update in: J Virol. 2022 Feb 23;96(4):e0196921. doi: 10.1128/jvi.01969-21. PMID: 34816260 Free PMC article. Updated. Preprint.

2

Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau.

Green KN, Steffan JS, Martinez-Coria H, Sun X, Schreiber SS, Thompson LM, LaFerla FM. Green KN, et al. J Neurosci. 2008 Nov 5;28(45):11500-10. doi: 10.1523/JNEUROSCI.3203-08.2008. J Neurosci. 2008. PMID: 18987186 Free PMC article.

3

Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss.

Hernandez MX, Jiang S, Cole TA, Chu SH, Fonseca MI, Fang MJ, Hohsfield LA, Torres MD, Green KN, Wetsel RA, Mortazavi A, Tenner AJ. Hernandez MX, et al. Among authors: green kn. Mol Neurodegener. 2017 Sep 18;12(1):66. doi: 10.1186/s13024-017-0210-z. Mol Neurodegener. 2017. PMID: 28923083 Free PMC article.

4

Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice.

Elmore MRP, Hohsfield LA, Kramár EA, Soreq L, Lee RJ, Pham ST, Najafi AR, Spangenberg EE, Wood MA, West BL, Green KN. Elmore MRP, et al. Among authors: green kn. Aging Cell. 2018 Dec;17(6):e12832. doi: 10.1111/acel.12832. Epub 2018 Oct 2. Aging Cell. 2018. PMID: 30276955 Free PMC article.

5

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.

Spangenberg E, Severson PL, Hohsfield LA, Crapser J, Zhang J, Burton EA, Zhang Y, Spevak W, Lin J, Phan NY, Habets G, Rymar A, Tsang G, Walters J, Nespi M, Singh P, Broome S, Ibrahim P, Zhang C, Bollag G, West BL, Green KN. Spangenberg E, et al. Among authors: green kn. Nat Commun. 2019 Aug 21;10(1):3758. doi: 10.1038/s41467-019-11674-z. Nat Commun. 2019. PMID: 31434879 Free PMC article.

6

Microglial depletion prevents extracellular matrix changes and striatal volume reduction in a model of Huntington's disease.

Crapser JD, Ochaba J, Soni N, Reidling JC, Thompson LM, Green KN. Crapser JD, et al. Among authors: green kn. Brain. 2020 Jan 1;143(1):266-288. doi: 10.1093/brain/awz363. Brain. 2020. PMID: 31848580 Free PMC article.

7

Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system.

Mangale V, Syage AR, Ekiz HA, Skinner DD, Cheng Y, Stone CL, Brown RM, O'Connell RM, Green KN, Lane TE. Mangale V, et al. Among authors: green kn. Glia. 2020 Nov;68(11):2345-2360. doi: 10.1002/glia.23844. Epub 2020 May 25. Glia. 2020. PMID: 32449994 Free PMC article.

8

Aging and Progression of Beta-Amyloid Pathology in Alzheimer's Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression.

Fernández-Mendívil C, Arreola MA, Hohsfield LA, Green KN, Lopez MG. Fernández-Mendívil C, et al. Among authors: green kn. Antioxidants (Basel). 2020 Jul 21;9(7):644. doi: 10.3390/antiox9070644. Antioxidants (Basel). 2020. PMID: 32708329 Free PMC article.

9

Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain.

Crapser JD, Spangenberg EE, Barahona RA, Arreola MA, Hohsfield LA, Green KN. Crapser JD, et al. Among authors: green kn. EBioMedicine. 2020 Aug;58:102919. doi: 10.1016/j.ebiom.2020.102919. Epub 2020 Jul 31. EBioMedicine. 2020. PMID: 32745992 Free PMC article.

10

To Kill a Microglia: A Case for CSF1R Inhibitors.

Green KN, Crapser JD, Hohsfield LA. Green KN, et al. Trends Immunol. 2020 Sep;41(9):771-784. doi: 10.1016/j.it.2020.07.001. Epub 2020 Aug 10. Trends Immunol. 2020. PMID: 32792173 Free PMC article. Review.

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