Wong KH - Search Results

1

Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing.

Sun H, Zeng J, Miao Z, Lei KC, Huang C, Hu L, Su SM, Chan UI, Miao K, Zhang X, Zhang A, Guo S, Chen S, Meng Y, Deng M, Hao W, Lei H, Lin Y, Yang Z, Tang D, Wong KH, Zhang XD, Xu X, Deng CX. Sun H, et al. Among authors: wong kh. Theranostics. 2021 Oct 25;11(20):9967-9987. doi: 10.7150/thno.63995. eCollection 2021. Theranostics. 2021. PMID: 34815798 Free PMC article.

2

Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans.

Leach MD, Farrer RA, Tan K, Miao Z, Walker LA, Cuomo CA, Wheeler RT, Brown AJ, Wong KH, Cowen LE. Leach MD, et al. Among authors: wong kh. Nat Commun. 2016 May 26;7:11704. doi: 10.1038/ncomms11704. Nat Commun. 2016. PMID: 27226156 Free PMC article.

3

Spheroidal formation preserves human stem cells for prolonged time under ambient conditions for facile storage and transportation.

Jiang B, Yan L, Miao Z, Li E, Wong KH, Xu RH. Jiang B, et al. Among authors: wong kh. Biomaterials. 2017 Jul;133:275-286. doi: 10.1016/j.biomaterials.2017.03.050. Epub 2017 Apr 18. Biomaterials. 2017. PMID: 28460350

4

BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition.

Zhang B, Lyu J, Liu Y, Wu C, Yang EJ, Pardeshi L, Tan K, Wong KH, Chen Q, Xu X, Deng CX, Shim JS. Zhang B, et al. Among authors: wong kh. Oncogene. 2018 Dec;37(49):6341-6356. doi: 10.1038/s41388-018-0408-8. Epub 2018 Jul 24. Oncogene. 2018. PMID: 30042414

5

NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation.

Miao K, Lei JH, Valecha MV, Zhang A, Xu J, Wang L, Lyu X, Chen S, Miao Z, Zhang X, Su SM, Shao F, Rajendran BK, Bao J, Zeng J, Sun H, Chen P, Tan K, Chen Q, Wong KH, Xu X, Deng CX. Miao K, et al. Among authors: wong kh. Nat Commun. 2020 Jun 26;11(1):3256. doi: 10.1038/s41467-020-16936-9. Nat Commun. 2020. PMID: 32591500 Free PMC article.

6

Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor.

Liu J, Adhav R, Miao K, Su SM, Mo L, Chan UI, Zhang X, Xu J, Li J, Shu X, Zeng J, Zhang X, Lyu X, Pardeshi L, Tan K, Sun H, Wong KH, Deng C, Xu X. Liu J, et al. Among authors: wong kh. Nat Commun. 2020 Sep 25;11(1):4875. doi: 10.1038/s41467-020-18637-9. Nat Commun. 2020. PMID: 32978388 Free PMC article.

7

Exploration of gastric neuroendocrine carcinoma (GNEC) specific signaling pathways involved in chemoresistance via transcriptome and in vitro analysis.

Xie J, Chen P, Xie H, Sun Y, Huang Z, Wei R, Miao Z, Wang Q, Zhang SD, Wong KH, Lin Y, Huang C, Kwok HF. Xie J, et al. Among authors: wong kh. Comput Struct Biotechnol J. 2020 Sep 20;18:2610-2620. doi: 10.1016/j.csbj.2020.09.016. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 33033581 Free PMC article.

8

Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel.

Wang H, Guo S, Kim SJ, Shao F, Ho JWK, Wong KU, Miao Z, Hao D, Zhao M, Xu J, Zeng J, Wong KH, Di L, Wong AH, Xu X, Deng CX. Wang H, et al. Among authors: wong kh, wong ku, wong ah. Theranostics. 2021 Jan 1;11(5):2442-2459. doi: 10.7150/thno.46460. eCollection 2021. Theranostics. 2021. PMID: 33500735 Free PMC article.

9

Chromatin profiling reveals heterogeneity in clinical isolates of the human pathogen Aspergillus fumigatus.

Colabardini AC, Wang F, Miao Z, Pardeshi L, Valero C, de Castro PA, Akiyama DY, Tan K, Nora LC, Silva-Rocha R, Marcet-Houben M, Gabaldón T, Fill T, Wong KH, Goldman GH. Colabardini AC, et al. Among authors: wong kh. PLoS Genet. 2022 Jan 10;18(1):e1010001. doi: 10.1371/journal.pgen.1010001. eCollection 2022 Jan. PLoS Genet. 2022. PMID: 35007279 Free PMC article.

10

Carbon Catabolite Repression Governs Diverse Physiological Processes and Development in Aspergillus nidulans.

Chen Y, Dong L, Alam MA, Pardeshi L, Miao Z, Wang F, Tan K, Hynes MJ, Kelly JM, Wong KH. Chen Y, et al. Among authors: wong kh. mBio. 2021 Feb 22;13(1):e0373421. doi: 10.1128/mbio.03734-21. Epub 2022 Feb 15. mBio. 2021. PMID: 35164551 Free PMC article.

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