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Inhibitors of bacterial RNA polymerase transcription complex.
Wenholz DS, Miller M, Dawson C, Bhadbhade M, Black DS, Griffith R, Dinh H, Cain A, Lewis P, Kumar N. Wenholz DS, et al. Among authors: cain a. Bioorg Chem. 2022 Jan;118:105481. doi: 10.1016/j.bioorg.2021.105481. Epub 2021 Nov 13. Bioorg Chem. 2022. PMID: 34801947
Platinum Cyclooctadiene Complexes with Activity against Gram-positive Bacteria.
Frei A, Ramu S, Lowe GJ, Dinh H, Semenec L, Elliott AG, Zuegg J, Deckers A, Jung N, Bräse S, Cain AK, Blaskovich MAT. Frei A, et al. Among authors: cain ak. ChemMedChem. 2021 Oct 15;16(20):3165-3171. doi: 10.1002/cmdc.202100157. Epub 2021 Jul 8. ChemMedChem. 2021. PMID: 34018686 Free PMC article.
A synthetic peptide mimic kills Candida albicans and synergistically prevents infection.
Schaefer S, Vij R, Sprague JL, Austermeier S, Dinh H, Judzewitsch PR, Müller-Loennies S, Lopes Silva T, Seemann E, Qualmann B, Hertweck C, Scherlach K, Gutsmann T, Cain AK, Corrigan N, Gresnigt MS, Boyer C, Lenardon MD, Brunke S. Schaefer S, et al. Among authors: cain ak. Nat Commun. 2024 Aug 9;15(1):6818. doi: 10.1038/s41467-024-50491-x. Nat Commun. 2024. PMID: 39122699 Free PMC article.
DksA is a conserved master regulator of stress response in Acinetobacter baumannii.
Maharjan RP, Sullivan GJ, Adams FG, Shah BS, Hawkey J, Delgado N, Semenec L, Dinh H, Li L, Short FL, Parkhill J, Paulsen IT, Barquist L, Eijkelkamp BA, Cain AK. Maharjan RP, et al. Among authors: cain ak. Nucleic Acids Res. 2023 Jul 7;51(12):6101-6119. doi: 10.1093/nar/gkad341. Nucleic Acids Res. 2023. PMID: 37158230 Free PMC article.
325 results