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Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation.
Gu F, Krüger A, Roggenkamp HG, Alpers R, Lodygin D, Jaquet V, Möckl F, Hernandez C LC, Winterberg K, Bauche A, Rosche A, Grasberger H, Kao JY, Schetelig D, Werner R, Schröder K, Carty M, Bowie AG, Huber S, Meier C, Mittrücker HW, Heeren J, Krause KH, Flügel A, Diercks BP, Guse AH. Gu F, et al. Among authors: werner r. Sci Signal. 2021 Nov 16;14(709):eabe3800. doi: 10.1126/scisignal.abe3800. Epub 2021 Nov 16. Sci Signal. 2021. PMID: 34784249
ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.
Diercks BP, Werner R, Weidemüller P, Czarniak F, Hernandez L, Lehmann C, Rosche A, Krüger A, Kaufmann U, Vaeth M, Failla AV, Zobiak B, Kandil FI, Schetelig D, Ruthenbeck A, Meier C, Lodygin D, Flügel A, Ren D, Wolf IMA, Feske S, Guse AH. Diercks BP, et al. Among authors: werner r. Sci Signal. 2018 Dec 18;11(561):eaat0358. doi: 10.1126/scisignal.aat0358. Sci Signal. 2018. PMID: 30563862 Free PMC article.
HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation.
Roggenkamp HG, Khansahib I, Hernandez C LC, Zhang Y, Lodygin D, Krüger A, Gu F, Möckl F, Löhndorf A, Wolters V, Woike D, Rosche A, Bauche A, Schetelig D, Werner R, Schlüter H, Failla AV, Meier C, Fliegert R, Walseth TF, Flügel A, Diercks BP, Guse AH. Roggenkamp HG, et al. Among authors: werner r. Sci Signal. 2021 Mar 23;14(675):eabd5647. doi: 10.1126/scisignal.abd5647. Sci Signal. 2021. PMID: 33758062
1,370 results