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Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid.
Kukat C, Davies KM, Wurm CA, Spåhr H, Bonekamp NA, Kühl I, Joos F, Polosa PL, Park CB, Posse V, Falkenberg M, Jakobs S, Kühlbrandt W, Larsson NG. Kukat C, et al. Among authors: bonekamp na. Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11288-93. doi: 10.1073/pnas.1512131112. Epub 2015 Aug 24. Proc Natl Acad Sci U S A. 2015. PMID: 26305956 Free PMC article.
SnapShot: Mitochondrial Nucleoid.
Bonekamp NA, Larsson NG. Bonekamp NA, et al. Cell. 2018 Jan 11;172(1-2):388-388.e1. doi: 10.1016/j.cell.2017.12.039. Cell. 2018. PMID: 29328920 Free article. Review.
Small-molecule inhibitors of human mitochondrial DNA transcription.
Bonekamp NA, Peter B, Hillen HS, Felser A, Bergbrede T, Choidas A, Horn M, Unger A, Di Lucrezia R, Atanassov I, Li X, Koch U, Menninger S, Boros J, Habenberger P, Giavalisco P, Cramer P, Denzel MS, Nussbaumer P, Klebl B, Falkenberg M, Gustafsson CM, Larsson NG. Bonekamp NA, et al. Nature. 2020 Dec;588(7839):712-716. doi: 10.1038/s41586-020-03048-z. Epub 2020 Dec 16. Nature. 2020. PMID: 33328633
Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity.
Sprenger HG, MacVicar T, Bahat A, Fiedler KU, Hermans S, Ehrentraut D, Ried K, Milenkovic D, Bonekamp N, Larsson NG, Nolte H, Giavalisco P, Langer T. Sprenger HG, et al. Nat Metab. 2021 May;3(5):636-650. doi: 10.1038/s42255-021-00385-9. Epub 2021 Apr 26. Nat Metab. 2021. PMID: 33903774 Free PMC article.
High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo.
Bonekamp NA, Jiang M, Motori E, Garcia Villegas R, Koolmeister C, Atanassov I, Mesaros A, Park CB, Larsson NG. Bonekamp NA, et al. Life Sci Alliance. 2021 Aug 30;4(11):e202101034. doi: 10.26508/lsa.202101034. Print 2021 Nov. Life Sci Alliance. 2021. PMID: 34462320 Free PMC article.
24 results