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Effects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer's Disease and Control Mice.
den Hoedt S, Crivelli SM, Leijten FPJ, Losen M, Stevens JAA, Mané-Damas M, de Vries HE, Walter J, Mirzaian M, Sijbrands EJG, Aerts JMFG, Verhoeven AJM, Martinez-Martinez P, Mulder MT. den Hoedt S, et al. Among authors: walter j. Front Aging Neurosci. 2021 Oct 27;13:765252. doi: 10.3389/fnagi.2021.765252. eCollection 2021. Front Aging Neurosci. 2021. PMID: 34776936 Free PMC article.
Altered Sphingolipid Balance in Capillary Cerebral Amyloid Angiopathy.
de Wit NM, Snkhchyan H, den Hoedt S, Wattimena D, de Vos R, Mulder MT, Walter J, Martinez-Martinez P, Hoozemans JJ, Rozemuller AJ, de Vries HE. de Wit NM, et al. Among authors: walter j. J Alzheimers Dis. 2017;60(3):795-807. doi: 10.3233/JAD-160551. J Alzheimers Dis. 2017. PMID: 27662305
Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels.
den Hoedt S, Janssen CIF, Astarita G, Piomelli D, Leijten FPJ, Crivelli SM, Verhoeven AJM, de Vries HE, Walter J, Martinez-Martinez P, Sijbrands EJG, Kiliaan AJ, Mulder MT. den Hoedt S, et al. Among authors: walter j. J Alzheimers Dis. 2017;60(3):769-781. doi: 10.3233/JAD-160739. J Alzheimers Dis. 2017. PMID: 28035926
Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model.
Bogie J, Hoeks C, Schepers M, Tiane A, Cuypers A, Leijten F, Chintapakorn Y, Suttiyut T, Pornpakakul S, Struik D, Kerksiek A, Liu HB, Hellings N, Martinez-Martinez P, Jonker JW, Dewachter I, Sijbrands E, Walter J, Hendriks J, Groen A, Staels B, Lütjohann D, Vanmierlo T, Mulder M. Bogie J, et al. Among authors: walter j. Sci Rep. 2019 Mar 20;9(1):4908. doi: 10.1038/s41598-019-41399-4. Sci Rep. 2019. PMID: 30894635 Free PMC article.
Sphingolipids in Alzheimer's disease, how can we target them?
Crivelli SM, Giovagnoni C, Visseren L, Scheithauer AL, de Wit N, den Hoedt S, Losen M, Mulder MT, Walter J, de Vries HE, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Among authors: walter j. Adv Drug Deliv Rev. 2020;159:214-231. doi: 10.1016/j.addr.2019.12.003. Epub 2020 Jan 3. Adv Drug Deliv Rev. 2020. PMID: 31911096 Review.
Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer's disease transgenic mice by functioning as a metabolic probe.
Crivelli SM, van Kruining D, Luo Q, Stevens JAA, Giovagnoni C, Paulus A, Bauwens M, Berkes D, de Vries HE, Mulder MT, Walter J, Waelkens E, Derua R, Swinnen JV, Dehairs J, Mottaghy FM, Losen M, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Among authors: walter j. Sci Rep. 2020 Nov 9;10(1):19354. doi: 10.1038/s41598-020-76335-4. Sci Rep. 2020. PMID: 33168861 Free PMC article.
CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease.
Crivelli SM, Luo Q, Stevens JAA, Giovagnoni C, van Kruining D, Bode G, den Hoedt S, Hobo B, Scheithauer AL, Walter J, Mulder MT, Exley C, Mold M, Mielke MM, De Vries HE, Wouters K, van den Hove DLA, Berkes D, Ledesma MD, Verhaagen J, Losen M, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Among authors: walter j. Alzheimers Res Ther. 2021 Feb 17;13(1):45. doi: 10.1186/s13195-021-00780-0. Alzheimers Res Ther. 2021. PMID: 33597019 Free PMC article.
FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer's disease expressing APOE4.
Crivelli SM, Luo Q, Kruining DV, Giovagnoni C, Mané-Damas M, den Hoedt S, Berkes D, De Vries HE, Mulder MT, Walter J, Waelkens E, Derua R, Swinnen JV, Dehairs J, Wijnands EPM, Bieberich E, Losen M, Martinez-Martinez P. Crivelli SM, et al. Among authors: walter j. Biomed Pharmacother. 2022 Aug;152:113240. doi: 10.1016/j.biopha.2022.113240. Epub 2022 Jun 9. Biomed Pharmacother. 2022. PMID: 35689862 Free article.
2,652 results