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Activation of EP4 receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function.
Konya V, Maric J, Jandl K, Luschnig P, Aringer I, Lanz I, Platzer W, Theiler A, Bärnthaler T, Frei R, Marsche G, Marsh LM, Olschewski A, Lippe IT, Heinemann A, Schuligoi R. Konya V, et al. Among authors: barnthaler t. Br J Pharmacol. 2015 Sep;172(18):4454-4468. doi: 10.1111/bph.13229. Epub 2015 Jul 31. Br J Pharmacol. 2015. PMID: 26103450 Free PMC article.
The Role of PGE2 in Alveolar Epithelial and Lung Microvascular Endothelial Crosstalk.
Bärnthaler T, Maric J, Platzer W, Konya V, Theiler A, Hasenöhrl C, Gottschalk B, Trautmann S, Schreiber Y, Graier WF, Schicho R, Marsche G, Olschewski A, Thomas D, Schuligoi R, Heinemann A. Bärnthaler T, et al. Sci Rep. 2017 Aug 11;7(1):7923. doi: 10.1038/s41598-017-08228-y. Sci Rep. 2017. PMID: 28801643 Free PMC article.
Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation.
Biasin V, Wygrecka M, Bärnthaler T, Jandl K, Jain PP, Bálint Z, Kovacs G, Leitinger G, Kolb-Lenz D, Kornmueller K, Peters F, Sinn K, Klepetko W, Heinemann A, Olschewski A, Becker-Pauly C, Kwapiszewska G. Biasin V, et al. Among authors: barnthaler t. Thromb Haemost. 2018 Oct;118(10):1790-1802. doi: 10.1055/s-0038-1670657. Epub 2018 Sep 20. Thromb Haemost. 2018. PMID: 30235485
Blockade of prostaglandin E2 receptor 4 ameliorates nephrotoxic serum nephritis.
Aringer I, Artinger K, Kirsch AH, Schabhüttl C, Jandl K, Bärnthaler T, Mooslechner AA, Herzog SA, Uhlig M, Kirsch A, Frank S, Banas M, Pollheimer M, Eller P, Rosenkranz AR, Heinemann A, Eller K. Aringer I, et al. Among authors: barnthaler t. Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1869-F1880. doi: 10.1152/ajprenal.00113.2018. Epub 2018 Oct 17. Am J Physiol Renal Physiol. 2018. PMID: 30332316 Free article.
Inhibiting eicosanoid degradation exerts antifibrotic effects in a pulmonary fibrosis mouse model and human tissue.
Bärnthaler T, Theiler A, Zabini D, Trautmann S, Stacher-Priehse E, Lanz I, Klepetko W, Sinn K, Flick H, Scheidl S, Thomas D, Olschewski H, Kwapiszewska G, Schuligoi R, Heinemann A. Bärnthaler T, et al. J Allergy Clin Immunol. 2020 Mar;145(3):818-833.e11. doi: 10.1016/j.jaci.2019.11.032. Epub 2019 Dec 5. J Allergy Clin Immunol. 2020. PMID: 31812575 Free article.
Lysophosphatidylcholines inhibit human eosinophil activation and suppress eosinophil migration in vivo.
Knuplez E, Curcic S, Theiler A, Bärnthaler T, Trakaki A, Trieb M, Holzer M, Heinemann A, Zimmermann R, Sturm EM, Marsche G. Knuplez E, et al. Among authors: barnthaler t. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jul;1865(7):158686. doi: 10.1016/j.bbalip.2020.158686. Epub 2020 Mar 11. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32171907 Free article.
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