Kaplowitz N - Search Results

1

Cyclical oxidation-reduction of the C3 position on bile acids catalyzed by rat hepatic 3 alpha-hydroxysteroid dehydrogenase. I. Studies with the purified enzyme, isolated rat hepatocytes, and inhibition by indomethacin.

Takikawa H, Stolz A, Kaplowitz N. Takikawa H, et al. Among authors: kaplowitz n. J Clin Invest. 1987 Sep;80(3):852-60. doi: 10.1172/JCI113143. J Clin Invest. 1987. PMID: 3476498 Free PMC article.

2

Oxidation and reduction of bile acid precursors by rat hepatic 3 alpha-hydroxysteroid dehydrogenase and inhibition by bile acids and indomethacin.

Takikawa H, Stolz A, Kuroki S, Kaplowitz N. Takikawa H, et al. Among authors: kaplowitz n. Biochim Biophys Acta. 1990 Apr 2;1043(2):153-6. doi: 10.1016/0005-2760(90)90289-a. Biochim Biophys Acta. 1990. PMID: 2317526

3

3 alpha-hydroxysteroid dehydrogenase activity of the Y' bile acid binders in rat liver cytosol. Identification, kinetics, and physiologic significance.

Stolz A, Takikawa H, Sugiyama Y, Kuhlenkamp J, Kaplowitz N. Stolz A, et al. Among authors: kaplowitz n. J Clin Invest. 1987 Feb;79(2):427-34. doi: 10.1172/JCI112829. J Clin Invest. 1987. PMID: 3468121 Free PMC article.

Rat Y' bile acid binders (33 kD) have been previously recognized as cytosolic bile acid binding proteins (Sugiyama, Y., T. Yamada, and N. Kaplowitz, 1983, J. Biol. Chem., 258:3602-3607). We have now determined that these Y' binders are 3 alpha-hydroxysteroid dehydro …

Rat Y' bile acid binders (33 kD) have been previously recognized as cytosolic bile acid binding proteins (Sugiyama, Y., T. Yamada, and N …

4

Cyclical oxidation-reduction of the C3 position on bile acids catalyzed by 3 alpha-hydroxysteroid dehydrogenase. II. Studies in the prograde and retrograde single-pass, perfused rat liver and inhibition by indomethacin.

Takikawa H, Ookhtens M, Stolz A, Kaplowitz N. Takikawa H, et al. Among authors: kaplowitz n. J Clin Invest. 1987 Sep;80(3):861-6. doi: 10.1172/JCI113144. J Clin Invest. 1987. PMID: 3476499 Free PMC article.

5

Effect of indomethacin on the uptake, metabolism and excretion of 3-oxocholic acid: studies in isolated hepatocytes and perfused rat liver.

Takikawa H, Fernandez-Checa JC, Kuhlenkamp J, Stolz A, Ookhtens M, Kaplowitz N. Takikawa H, et al. Among authors: kaplowitz n. Biochim Biophys Acta. 1991 Jul 30;1084(3):247-50. doi: 10.1016/0005-2760(91)90065-p. Biochim Biophys Acta. 1991. PMID: 1888771

6

Relationship between the newly identified bile acid binder and bile acid oxidoreductases in human liver.

Takikawa H, Stolz A, Sugiyama Y, Yoshida H, Yamanaka M, Kaplowitz N. Takikawa H, et al. Among authors: kaplowitz n. J Biol Chem. 1990 Feb 5;265(4):2132-6. J Biol Chem. 1990. PMID: 2153675 Free article.

Several enzymes including 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD), 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD), 3-ketosteroid reductase, and dihydrodiol dehydrogenase eluted mainly in the 30,000-40,000 Mr fractions known to contain the newly identified bile acid b …

Several enzymes including 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD), 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD), 3-ketosteroi …

7

Comparison of the effects of bile acids and GSH on the fluorescence of bound 1-anilino-8-naphthalene sulfonate and the enzymatic activity of cationic and neutral human hepatic GSH S-transferases.

Takikawa H, Sugiyama Y, Kaplowitz N. Takikawa H, et al. Among authors: kaplowitz n. Biochim Biophys Acta. 1988 Apr 28;954(1):37-43. doi: 10.1016/0167-4838(88)90052-0. Biochim Biophys Acta. 1988. PMID: 3358937

8

Comparison of the binding sites of GSH S-transferases of the Ya- and Yb-subunit classes: effect of glutathione on the binding of bile acids.

Takikawa H, Kaplowitz N. Takikawa H, et al. Among authors: kaplowitz n. J Lipid Res. 1988 Mar;29(3):279-86. J Lipid Res. 1988. PMID: 3379340 Free article.

9

Purification of a 32.5 kDa monomeric sulfotransferase from rat liver with activity for bile acids and phenolic steroids.

Takikawa H, Stolz A, Kaplowitz N. Takikawa H, et al. Among authors: kaplowitz n. FEBS Lett. 1986 Oct 27;207(2):193-7. doi: 10.1016/0014-5793(86)81487-9. FEBS Lett. 1986. PMID: 3464463 Free article.

10

Binding of bile acids by glutathione S-transferases from rat liver.

Takikawa H, Sugiyama Y, Kaplowitz N. Takikawa H, et al. Among authors: kaplowitz n. J Lipid Res. 1986 Sep;27(9):955-66. J Lipid Res. 1986. PMID: 3783048 Free article.

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