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Accelerating clinical trial implementation in the context of the COVID-19 pandemic: challenges, lessons learned and recommendations from DisCoVeRy and the EU-SolidAct EU response group.
EU-Response investigators group; Diallo A, Trøseid M, Simensen VC, Boston A, Demotes J, Olsen IC, Chung F, Paiva JA, Hites M, Ader F, Arribas JR, Baratt-Due A, Melien Ø, Tacconelli E, Staub T, Greil R, Tsiodras S, Briel M, Esperou H, Mentré F, Eustace J, Saillard J, Delmas C, LeMestre S, Dumousseaux M, Costagliola D, Røttingen JA, Yazdanpanah Y. EU-Response investigators group, et al. Among authors: demotes j. Clin Microbiol Infect. 2022 Jan;28(1):1-5. doi: 10.1016/j.cmi.2021.10.011. Epub 2021 Nov 8. Clin Microbiol Infect. 2022. PMID: 34763056 Free PMC article. No abstract available.
Closing the cycle of innovation in healthcare in Europe.
Hulstaert F, Ruether A, Demotes J, Melien Ø. Hulstaert F, et al. Among authors: demotes j. Int J Technol Assess Health Care. 2020 Apr;36(2):75-79. doi: 10.1017/S0266462319003532. Epub 2020 Jan 17. Int J Technol Assess Health Care. 2020. PMID: 31948497
Biomarker Research and Development for Coronavirus Disease 2019 (COVID-19): European Medical Research Infrastructures Call for Global Coordination.
Oldoni E, van Gool A, García Bermejo L, Scherer A, Mayrhofer MT, Florindi F, Demotes J, Kubiak C, Fauvel AC, Bietrix F, Ussi A, Andreu AL. Oldoni E, et al. Among authors: demotes j. Clin Infect Dis. 2021 May 18;72(10):1838-1842. doi: 10.1093/cid/ciaa1250. Clin Infect Dis. 2021. PMID: 33091118 Free PMC article.
Study designs for clinical trials applied to personalised medicine: a scoping review.
Superchi C, Brion Bouvier F, Gerardi C, Carmona M, San Miguel L, Sánchez-Gómez LM, Imaz-Iglesia I, Garcia P, Demotes J, Banzi R, Porcher R; PERMIT Group. Superchi C, et al. Among authors: demotes j. BMJ Open. 2022 May 6;12(5):e052926. doi: 10.1136/bmjopen-2021-052926. BMJ Open. 2022. PMID: 35523482 Free PMC article. Review.
PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment.
Reinink H, de Jonge JC, Bath PM, van de Beek D, Berge E, Borregaard S, Ciccone A, Csiba L, Demotes J, Dippel DW, Kõrv J, Kurkowska-Jastrzebska I, Lees KR, Macleod MR, Ntaios G, Randall G, Thomalla G, van der Worp HB. Reinink H, et al. Among authors: demotes j. Eur Stroke J. 2018 Sep;3(3):291-298. doi: 10.1177/2396987318772687. Epub 2018 Apr 30. Eur Stroke J. 2018. PMID: 30246150 Free PMC article.
EuroHYP-1: European multicenter, randomized, phase III clinical trial of therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke.
van der Worp HB, Macleod MR, Bath PM, Demotes J, Durand-Zaleski I, Gebhardt B, Gluud C, Kollmar R, Krieger DW, Lees KR, Molina C, Montaner J, Roine RO, Petersson J, Staykov D, Szabo I, Wardlaw JM, Schwab S; EuroHYP-1 investigators. van der Worp HB, et al. Among authors: demotes j. Int J Stroke. 2014 Jul;9(5):642-5. doi: 10.1111/ijs.12294. Epub 2014 May 15. Int J Stroke. 2014. PMID: 24828363 Clinical Trial.
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