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Depletion of Human Papilloma Virus E6- and E7-Oncoprotein-Specific T-Cell Responses in Women Living With HIV.
Mbuya W, Held K, Mcharo RD, Haule A, Mhizde J, Mnkai J, Mahenge A, Mwakatima M, Sembo M, Mwalongo W, Agrea P, Hoelscher M, Maboko L, Saathoff E, Geisenberger O, Rwegoshora F, Torres L, Koup RA, Kroidl A, Chachage M, Geldmacher C. Mbuya W, et al. Among authors: koup ra. Front Immunol. 2021 Oct 25;12:742861. doi: 10.3389/fimmu.2021.742861. eCollection 2021. Front Immunol. 2021. PMID: 34759925 Free PMC article.
Evidence for increased T cell turnover and decreased thymic output in HIV infection.
Douek DC, Betts MR, Hill BJ, Little SJ, Lempicki R, Metcalf JA, Casazza J, Yoder C, Adelsberger JW, Stevens RA, Baseler MW, Keiser P, Richman DD, Davey RT, Koup RA. Douek DC, et al. Among authors: koup ra. J Immunol. 2001 Dec 1;167(11):6663-8. doi: 10.4049/jimmunol.167.11.6663. J Immunol. 2001. PMID: 11714838
Vaccination in humans generates broad T cell cytokine responses.
De Rosa SC, Lu FX, Yu J, Perfetto SP, Falloon J, Moser S, Evans TG, Koup R, Miller CJ, Roederer M. De Rosa SC, et al. J Immunol. 2004 Nov 1;173(9):5372-80. doi: 10.4049/jimmunol.173.9.5372. J Immunol. 2004. PMID: 15494483
PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection.
Petrovas C, Casazza JP, Brenchley JM, Price DA, Gostick E, Adams WC, Precopio ML, Schacker T, Roederer M, Douek DC, Koup RA. Petrovas C, et al. Among authors: koup ra. J Exp Med. 2006 Oct 2;203(10):2281-92. doi: 10.1084/jem.20061496. Epub 2006 Sep 5. J Exp Med. 2006. PMID: 16954372 Free PMC article.
SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection.
Petrovas C, Price DA, Mattapallil J, Ambrozak DR, Geldmacher C, Cecchinato V, Vaccari M, Tryniszewska E, Gostick E, Roederer M, Douek DC, Morgan SH, Davis SJ, Franchini G, Koup RA. Petrovas C, et al. Among authors: koup ra. Blood. 2007 Aug 1;110(3):928-36. doi: 10.1182/blood-2007-01-069112. Epub 2007 Apr 17. Blood. 2007. PMID: 17440051 Free PMC article.
444 results