Zheng M - Search Results

1

SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade.

Wang X, Ni J, You Y, Feng G, Zhang S, Bao W, Hou H, Li H, Liu L, Zheng M, Wang Y, Zhou H, Shen W, Shen X. Wang X, et al. Among authors: zheng m. EMBO J. 2021 Dec 15;40(24):e108080. doi: 10.15252/embj.2021108080. Epub 2021 Nov 8. EMBO J. 2021. PMID: 34747049 Free PMC article.

2

SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC.

Zhang S, Yang Z, Bao W, Liu L, You Y, Wang X, Shao L, Fu W, Kou X, Shen W, Yuan C, Hu B, Dang W, Nandakumar KS, Jiang H, Zheng M, Shen X. Zhang S, et al. Among authors: zheng m. Autophagy. 2020 Apr;16(4):735-749. doi: 10.1080/15548627.2019.1632122. Epub 2019 Jul 4. Autophagy. 2020. PMID: 31208298 Free PMC article.

3

Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation.

Li X, Li Z, Wu X, Xiong Z, Yang T, Fu Z, Liu X, Tan X, Zhong F, Wan X, Wang D, Ding X, Yang R, Hou H, Li C, Liu H, Chen K, Jiang H, Zheng M. Li X, et al. Among authors: zheng m. J Med Chem. 2020 Aug 27;63(16):8723-8737. doi: 10.1021/acs.jmedchem.9b00855. Epub 2019 Aug 15. J Med Chem. 2020. PMID: 31364850

4

Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-Dependent TFEB Signaling Pathway.

You Y, Bao WL, Zhang SL, Li HD, Li H, Dang WZ, Zou SL, Cao XY, Wang X, Liu LX, Jiang H, Qu LF, Zheng M, Shen X. You Y, et al. Among authors: zheng m. Circ Res. 2020 Jul 31;127(4):534-549. doi: 10.1161/CIRCRESAHA.119.315516. Epub 2020 Apr 22. Circ Res. 2020. PMID: 32316875

5

Discovery of triazoloquinoxaline as novel STING agonists via structure-based virtual screening.

Hou H, Yang R, Liu X, Wu X, Zhang S, Chen K, Zheng M. Hou H, et al. Among authors: zheng m. Bioorg Chem. 2020 Jul;100:103958. doi: 10.1016/j.bioorg.2020.103958. Epub 2020 May 20. Bioorg Chem. 2020. PMID: 32470762

6

Cytoplasmic DNA sensing by KU complex in aged CD4⁺ T cell potentiates T cell activation and aging-related autoimmune inflammation.

Wang Y, Fu Z, Li X, Liang Y, Pei S, Hao S, Zhu Q, Yu T, Pei Y, Yuan J, Ye J, Fu J, Xu J, Hong J, Yang R, Hou H, Huang X, Peng C, Zheng M, Xiao Y. Wang Y, et al. Among authors: zheng m. Immunity. 2021 Apr 13;54(4):632-647.e9. doi: 10.1016/j.immuni.2021.02.003. Epub 2021 Mar 4. Immunity. 2021. PMID: 33667382 Free article.

7

Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation.

Bao W, Liu X, You Y, Hou H, Wang X, Zhang S, Li H, Feng G, Cao X, Jiang H, Zheng M, Shen X. Bao W, et al. Among authors: zheng m. Pharmacol Res. 2021 Jul;169:105679. doi: 10.1016/j.phrs.2021.105679. Epub 2021 May 16. Pharmacol Res. 2021. PMID: 34010669

8

Drug target inference by mining transcriptional data using a novel graph convolutional network framework.

Zhong F, Wu X, Yang R, Li X, Wang D, Fu Z, Liu X, Wan X, Yang T, Fan Z, Zhang Y, Luo X, Chen K, Zhang S, Jiang H, Zheng M. Zhong F, et al. Among authors: zheng m. Protein Cell. 2022 Apr;13(4):281-301. doi: 10.1007/s13238-021-00885-0. Epub 2021 Oct 22. Protein Cell. 2022. PMID: 34677780 Free PMC article.

9

Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation.

Tan X, Li C, Yang R, Zhao S, Li F, Li X, Chen L, Wan X, Liu X, Yang T, Tong X, Xu T, Cui R, Jiang H, Zhang S, Liu H, Zheng M. Tan X, et al. Among authors: zheng m. J Med Chem. 2022 Jan 13;65(1):103-119. doi: 10.1021/acs.jmedchem.1c01205. Epub 2021 Nov 25. J Med Chem. 2022. PMID: 34821145

10

Graph neural network approaches for drug-target interactions.

Zhang Z, Chen L, Zhong F, Wang D, Jiang J, Zhang S, Jiang H, Zheng M, Li X. Zhang Z, et al. Among authors: zheng m. Curr Opin Struct Biol. 2022 Apr;73:102327. doi: 10.1016/j.sbi.2021.102327. Epub 2022 Jan 21. Curr Opin Struct Biol. 2022. PMID: 35074533 Review.

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