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The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds.
Brecklinghaus T, Albrecht W, Kappenberg F, Duda J, Vartak N, Edlund K, Marchan R, Ghallab A, Cadenas C, Günther G, Leist M, Zhang M, Gardner I, Reinders J, Russel FG, Foster AJ, Williams DP, Damle-Vartak A, Grandits M, Ecker G, Kittana N, Rahnenführer J, Hengstler JG. Brecklinghaus T, et al. Among authors: foster aj. Chem Biol Interact. 2022 Jan 5;351:109728. doi: 10.1016/j.cbi.2021.109728. Epub 2021 Oct 27. Chem Biol Interact. 2022. PMID: 34717914 Free article.
Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study.
Bell CC, Dankers ACA, Lauschke VM, Sison-Young R, Jenkins R, Rowe C, Goldring CE, Park K, Regan SL, Walker T, Schofield C, Baze A, Foster AJ, Williams DP, van de Ven AWM, Jacobs F, Houdt JV, Lähteenmäki T, Snoeys J, Juhila S, Richert L, Ingelman-Sundberg M. Bell CC, et al. Among authors: foster aj. Toxicol Sci. 2018 Apr 1;162(2):655-666. doi: 10.1093/toxsci/kfx289. Toxicol Sci. 2018. PMID: 29329425 Free PMC article.
Predicting Drug-Induced Liver Injury with Bayesian Machine Learning.
Williams DP, Lazic SE, Foster AJ, Semenova E, Morgan P. Williams DP, et al. Among authors: foster aj. Chem Res Toxicol. 2020 Jan 21;33(1):239-248. doi: 10.1021/acs.chemrestox.9b00264. Epub 2019 Oct 2. Chem Res Toxicol. 2020. PMID: 31535850
Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.
Foster AJ, Chouhan B, Regan SL, Rollison H, Amberntsson S, Andersson LC, Srivastava A, Darnell M, Cairns J, Lazic SE, Jang KJ, Petropolis DB, Kodella K, Rubins JE, Williams D, Hamilton GA, Ewart L, Morgan P. Foster AJ, et al. Arch Toxicol. 2019 Apr;93(4):1021-1037. doi: 10.1007/s00204-019-02427-4. Epub 2019 Mar 26. Arch Toxicol. 2019. PMID: 30915487
Introducing an automated high content confocal imaging approach for Organs-on-Chips.
Peel S, Corrigan AM, Ehrhardt B, Jang KJ, Caetano-Pinto P, Boeckeler M, Rubins JE, Kodella K, Petropolis DB, Ronxhi J, Kulkarni G, Foster AJ, Williams D, Hamilton GA, Ewart L. Peel S, et al. Among authors: foster aj. Lab Chip. 2019 Jan 29;19(3):410-421. doi: 10.1039/c8lc00829a. Lab Chip. 2019. PMID: 30663729
93 results