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Page 1
Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential.
Bujotzek A, Tiefenthaler G, Lariviere L, D'Andrea L, Marquez EA, Rudloff I, Cho SX, Deen NS, Richter W, Regenass-Lechner F, Poehler A, Whisstock JC, Sydow-Andersen J, Reiser X, Schuster S, Neubauer J, Hoepfl S, Richter K, Nold MF, Nold-Petry CA, Schumacher F, Ellisdon AM. Bujotzek A, et al. Among authors: deen ns. Cell Chem Biol. 2022 Apr 21;29(4):586-596.e4. doi: 10.1016/j.chembiol.2021.10.004. Epub 2021 Oct 25. Cell Chem Biol. 2022. PMID: 34699747 Free article.
Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation.
Lang T, Lee JPW, Elgass K, Pinar AA, Tate MD, Aitken EH, Fan H, Creed SJ, Deen NS, Traore DAK, Mueller I, Stanisic D, Baiwog FS, Skene C, Wilce MCJ, Mansell A, Morand EF, Harris J. Lang T, et al. Among authors: deen ns. Nat Commun. 2018 Jun 8;9(1):2223. doi: 10.1038/s41467-018-04581-2. Nat Commun. 2018. PMID: 29884801 Free PMC article.
Mitophagy and the release of inflammatory cytokines.
Harris J, Deen N, Zamani S, Hasnat MA. Harris J, et al. Mitochondrion. 2018 Jul;41:2-8. doi: 10.1016/j.mito.2017.10.009. Epub 2017 Oct 26. Mitochondrion. 2018. PMID: 29107116 Review.
Rediscovering MIF: New Tricks for an Old Cytokine.
Harris J, VanPatten S, Deen NS, Al-Abed Y, Morand EF. Harris J, et al. Among authors: deen ns. Trends Immunol. 2019 May;40(5):447-462. doi: 10.1016/j.it.2019.03.002. Epub 2019 Apr 5. Trends Immunol. 2019. PMID: 30962001 Review.