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Page 1
Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma.
Frede J, Anand P, Sotudeh N, Pinto RA, Nair MS, Stuart H, Yee AJ, Vijaykumar T, Waldschmidt JM, Potdar S, Kloeber JA, Kokkalis A, Dimitrova V, Mann M, Laubach JP, Richardson PG, Anderson KC, Raje NS, Knoechel B, Lohr JG. Frede J, et al. Among authors: kloeber ja. Nat Cell Biol. 2021 Nov;23(11):1199-1211. doi: 10.1038/s41556-021-00766-y. Epub 2021 Oct 21. Nat Cell Biol. 2021. PMID: 34675390 Free PMC article.
Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing.
Guo G, Raje NS, Seifer C, Kloeber J, Isenhart R, Ha G, Yee AJ, O'Donnell EK, Tai YT, Richardson PG, Bianchi G, Laubach JP, Warren D, Gemme E, Voisine J, Frede J, Kokkalis A, Yun H, Dimitrova V, Vijaykumar T, Meyerson M, Munshi NC, Anderson KC, Knoechel B, Lohr JG. Guo G, et al. Leukemia. 2018 Aug;32(8):1838-1841. doi: 10.1038/s41375-018-0115-z. Epub 2018 Mar 27. Leukemia. 2018. PMID: 29749395 Free PMC article. Clinical Trial. No abstract available.
Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL.
Anand P, Guillaumet-Adkins A, Dimitrova V, Yun H, Drier Y, Sotudeh N, Rogers A, Ouseph MM, Nair M, Potdar S, Isenhart R, Kloeber JA, Vijaykumar T, Niu L, Vincent T, Guo G, Frede J, Harris MH, Place AE, Silverman LB, Teachey DT, Lane AA, DeAngelo DJ, Aster JC, Bernstein BE, Lohr JG, Knoechel B. Anand P, et al. Among authors: kloeber ja. Blood. 2021 May 6;137(18):2463-2480. doi: 10.1182/blood.2019004547. Blood. 2021. PMID: 33227818 Free PMC article.
Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in BRAF-Mutated Multiple Myeloma.
Waldschmidt JM, Kloeber JA, Anand P, Frede J, Kokkalis A, Dimitrova V, Potdar S, Nair MS, Vijaykumar T, Im NG, Guillaumet-Adkins A, Chopra N, Stuart H, Budano L, Sotudeh N, Guo G, Grassberger C, Yee AJ, Laubach JP, Richardson PG, Anderson KC, Raje NS, Knoechel B, Lohr JG. Waldschmidt JM, et al. Among authors: kloeber ja. Clin Cancer Res. 2021 Dec 1;27(23):6432-6444. doi: 10.1158/1078-0432.CCR-21-2040. Epub 2021 Sep 13. Clin Cancer Res. 2021. PMID: 34518309 Free PMC article.
Cell-free DNA for the detection of emerging treatment failure in relapsed/ refractory multiple myeloma.
Waldschmidt JM, Yee AJ, Vijaykumar T, Pinto RA, Frede J, Anand P, Bianchi G, Guo G, Potdar S, Seifer C, Nair MS, Kokkalis A, Kloeber JA, Shapiro S, Budano L, Mann M, Friedman R, Lipe B, Campagnaro E, O'Donnell EK, Zhang CZ, Laubach JP, Munshi NC, Richardson PG, Anderson KC, Raje NS, Knoechel B, Lohr JG. Waldschmidt JM, et al. Among authors: kloeber ja. Leukemia. 2022 Apr;36(4):1078-1087. doi: 10.1038/s41375-021-01492-y. Epub 2022 Jan 13. Leukemia. 2022. PMID: 35027656 Free PMC article. Clinical Trial.
ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection.
Zhao F, Kim W, Gao H, Liu C, Zhang Y, Chen Y, Deng M, Zhou Q, Huang J, Hu Q, Chen SH, Nowsheen S, Kloeber JA, Qin B, Yin P, Tu X, Guo G, Qin S, Zhang C, Gao M, Luo K, Liu Y, Lou Z, Yuan J. Zhao F, et al. Among authors: kloeber ja. Nat Cell Biol. 2021 Aug;23(8):894-904. doi: 10.1038/s41556-021-00723-9. Epub 2021 Aug 5. Nat Cell Biol. 2021. PMID: 34354233
USP13 regulates the replication stress response by deubiquitinating TopBP1.
Kim W, Zhao F, Gao H, Qin S, Hou J, Deng M, Kloeber JA, Huang J, Zhou Q, Guo G, Gao M, Zeng X, Zhu S, Tu X, Wu Z, Zhang Y, Yin P, Kaufmann SH, Luo K, Lou Z. Kim W, et al. Among authors: kloeber ja. DNA Repair (Amst). 2021 Apr;100:103063. doi: 10.1016/j.dnarep.2021.103063. Epub 2021 Feb 6. DNA Repair (Amst). 2021. PMID: 33592542 Free PMC article.
30 results