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Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants.
Hegron A, Huh E, Deupi X, Sokrat B, Gao W, Le Gouill C, Canouil M, Boissel M, Charpentier G, Roussel R, Balkau B, Froguel P, Plouffe B, Bonnefond A, Lichtarge O, Jockers R, Bouvier M. Hegron A, et al. Among authors: lichtarge o. ACS Pharmacol Transl Sci. 2021 Sep 1;4(5):1614-1627. doi: 10.1021/acsptsci.1c00157. eCollection 2021 Oct 8. ACS Pharmacol Transl Sci. 2021. PMID: 34661078 Free PMC article.
Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.
Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro G. Benredjem B, et al. Among authors: lichtarge o. Nat Commun. 2019 Sep 9;10(1):4075. doi: 10.1038/s41467-019-11875-6. Nat Commun. 2019. PMID: 31501422 Free PMC article.
Author Correction: Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.
Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro G. Benredjem B, et al. Among authors: lichtarge o. Nat Commun. 2020 Apr 16;11(1):1929. doi: 10.1038/s41467-020-15945-y. Nat Commun. 2020. PMID: 32300106 Free PMC article.
Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants.
Plouffe B, Karamitri A, Flock T, Gallion JM, Houston S, Daly CA, Bonnefond A, Guillaume JL, Le Gouill C, Froguel P, Lichtarge O, Deupi X, Jockers R, Bouvier M. Plouffe B, et al. Among authors: lichtarge o. ACS Pharmacol Transl Sci. 2022 Jan 25;5(2):89-101. doi: 10.1021/acsptsci.1c00239. eCollection 2022 Feb 11. ACS Pharmacol Transl Sci. 2022. PMID: 35846981 Free PMC article.
199 results