Thirusangu P - Search Results

1

Targeting LRRC15 Inhibits Metastatic Dissemination of Ovarian Cancer.

Ray U, Jung DB, Jin L, Xiao Y, Dasari S, Sarkar Bhattacharya S, Thirusangu P, Staub JK, Roy D, Roy B, Weroha SJ, Hou X, Purcell JW, Bakkum-Gamez JN, Kaufmann SH, Kannan N, Mitra AK, Shridhar V. Ray U, et al. Among authors: thirusangu p. Cancer Res. 2022 Mar 15;82(6):1038-1054. doi: 10.1158/0008-5472.CAN-21-0622. Cancer Res. 2022. PMID: 34654724 Free PMC article.

2

PFKFB3 inhibition reprograms malignant pleural mesothelioma to nutrient stress-induced macropinocytosis and ER stress as independent binary adaptive responses.

Sarkar Bhattacharya S, Thirusangu P, Jin L, Roy D, Jung D, Xiao Y, Staub J, Roy B, Molina JR, Shridhar V. Sarkar Bhattacharya S, et al. Among authors: thirusangu p. Cell Death Dis. 2019 Sep 27;10(10):725. doi: 10.1038/s41419-019-1916-3. Cell Death Dis. 2019. PMID: 31562297 Free PMC article.

3

Repurposing quinacrine for treatment-refractory cancer.

Oien DB, Pathoulas CL, Ray U, Thirusangu P, Kalogera E, Shridhar V. Oien DB, et al. Among authors: thirusangu p. Semin Cancer Biol. 2021 Jan;68:21-30. doi: 10.1016/j.semcancer.2019.09.021. Epub 2019 Sep 25. Semin Cancer Biol. 2021. PMID: 31562955 Free article. Review.

4

Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer.

Xiao Y, Jin L, Deng C, Guan Y, Kalogera E, Ray U, Thirusangu P, Staub J, Sarkar Bhattacharya S, Xu H, Fang X, Shridhar V. Xiao Y, et al. Among authors: thirusangu p. Oncogene. 2021 Feb;40(8):1409-1424. doi: 10.1038/s41388-020-01621-4. Epub 2021 Jan 8. Oncogene. 2021. PMID: 33420377 Free PMC article.

5

Quinacrine-Induced Autophagy in Ovarian Cancer Triggers Cathepsin-L Mediated Lysosomal/Mitochondrial Membrane Permeabilization and Cell Death.

Thirusangu P, Pathoulas CL, Ray U, Xiao Y, Staub J, Jin L, Khurana A, Shridhar V. Thirusangu P, et al. Cancers (Basel). 2021 Apr 21;13(9):2004. doi: 10.3390/cancers13092004. Cancers (Basel). 2021. PMID: 33919392 Free PMC article.

6

Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization.

Ray U, Roy D, Jin L, Thirusangu P, Staub J, Xiao Y, Kalogera E, Wahner Hendrickson AE, Cullen GD, Goergen K, Oberg AL, Shridhar V. Ray U, et al. Among authors: thirusangu p. J Exp Clin Cancer Res. 2021 Jun 3;40(1):182. doi: 10.1186/s13046-021-01985-9. J Exp Clin Cancer Res. 2021. PMID: 34082797 Free PMC article.

7

Quinacrine Induces Nucleolar Stress in Treatment-Refractory Ovarian Cancer Cell Lines.

Oien DB, Ray U, Pathoulas CL, Jin L, Thirusangu P, Jung D, Kumka JE, Xiao Y, Sarkar Bhattacharya S, Montoya D, Chien J, Shridhar V. Oien DB, et al. Among authors: thirusangu p. Cancers (Basel). 2021 Sep 16;13(18):4645. doi: 10.3390/cancers13184645. Cancers (Basel). 2021. PMID: 34572872 Free PMC article.

8

Exploiting LRRC15 as a Novel Therapeutic Target in Cancer.

Ray U, Pathoulas CL, Thirusangu P, Purcell JW, Kannan N, Shridhar V. Ray U, et al. Among authors: thirusangu p. Cancer Res. 2022 May 3;82(9):1675-1681. doi: 10.1158/0008-5472.CAN-21-3734. Cancer Res. 2022. PMID: 35260879 Free PMC article. Review.

9

PFKFB3 works on the FAK-STAT3-SOX2 axis to regulate the stemness in MPM.

Sarkar Bhattacharya S, Thirusangu P, Jin L, Staub J, Shridhar V, Molina JR. Sarkar Bhattacharya S, et al. Among authors: thirusangu p. Br J Cancer. 2022 Oct;127(7):1352-1364. doi: 10.1038/s41416-022-01867-7. Epub 2022 Jul 6. Br J Cancer. 2022. PMID: 35794237 Free PMC article.

10

PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinoma.

Thirusangu P, Ray U, Sarkar Bhattacharya S, Oien DB, Jin L, Staub J, Kannan N, Molina JR, Shridhar V. Thirusangu P, et al. Oncogene. 2022 Aug;41(33):4003-4017. doi: 10.1038/s41388-022-02391-x. Epub 2022 Jul 8. Oncogene. 2022. PMID: 35804016 Free PMC article.

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