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Oral delivery of ambrisentan-loaded lipid-core nanocapsules as a novel approach for the treatment of pulmonary arterial hypertension.
Zancan LR, Bruinsmann FA, Paese K, Türck P, Bahr A, Zimmer A, Carraro CC, Schenkel PC, Belló-Klein A, Schwertz CI, Driemeier D, Pohlmann AR, Guterres SS. Zancan LR, et al. Among authors: zimmer a. Int J Pharm. 2021 Dec 15;610:121181. doi: 10.1016/j.ijpharm.2021.121181. Epub 2021 Oct 12. Int J Pharm. 2021. PMID: 34653563
Stilbenoid pterostilbene complexed with cyclodextrin preserves left ventricular function after myocardial infarction in rats: possible involvement of thiol proteins and modulation of phosphorylated GSK-3β.
Lacerda D, Ortiz V, Türck P, Campos-Carraro C, Zimmer A, Teixeira R, Bianchi S, de Castro AL, Schenkel PC, Belló-Klein A, Bassani VL, da Rosa Araujo AS. Lacerda D, et al. Among authors: zimmer a. Free Radic Res. 2018 Sep;52(9):988-999. doi: 10.1080/10715762.2018.1506115. Epub 2018 Sep 11. Free Radic Res. 2018. PMID: 30203709
Role of inflammation, oxidative stress, and autonomic nervous system activation during the development of right and left cardiac remodeling in experimental pulmonary arterial hypertension.
Zimmer A, Teixeira RB, Bonetto JHP, Bahr AC, Türck P, de Castro AL, Campos-Carraro C, Visioli F, Fernandes-Piedras TR, Casali KR, Scassola CMC, Baldo G, Araujo AS, Singal P, Belló-Klein A. Zimmer A, et al. Mol Cell Biochem. 2020 Jan;464(1-2):93-109. doi: 10.1007/s11010-019-03652-2. Epub 2019 Nov 14. Mol Cell Biochem. 2020. PMID: 31728802
The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity.
Zimmer A, Teixeira RB, Constantin RL, Campos-Carraro C, Aparicio Cordero EA, Ortiz VD, Donatti L, Gonzalez E, Bahr AC, Visioli F, Baldo G, Luz de Castro A, Araujo AS, Belló-Klein A. Zimmer A, et al. Eur J Pharmacol. 2021 Jan 15;891:173699. doi: 10.1016/j.ejphar.2020.173699. Epub 2020 Nov 5. Eur J Pharmacol. 2021. PMID: 33160936
979 results