Toso EA - Search Results

1

Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma.

Bosnakovski D, Ener ET, Cooper MS, Gearhart MD, Knights KA, Xu NC, Palumbo CA, Toso EA, Marsh GP, Maple HJ, Kyba M. Bosnakovski D, et al. Among authors: toso ea. Oncogenesis. 2021 Oct 12;10(10):68. doi: 10.1038/s41389-021-00357-4. Oncogenesis. 2021. PMID: 34642317 Free PMC article.

2

A focal domain of extreme demethylation within D4Z4 in FSHD2.

Hartweck LM, Anderson LJ, Lemmers RJ, Dandapat A, Toso EA, Dalton JC, Tawil R, Day JW, van der Maarel SM, Kyba M. Hartweck LM, et al. Among authors: toso ea. Neurology. 2013 Jan 22;80(4):392-9. doi: 10.1212/WNL.0b013e31827f075c. Epub 2013 Jan 2. Neurology. 2013. PMID: 23284062 Free PMC article.

3

High-throughput screening identifies inhibitors of DUX4-induced myoblast toxicity.

Bosnakovski D, Choi SH, Strasser JM, Toso EA, Walters MA, Kyba M. Bosnakovski D, et al. Among authors: toso ea. Skelet Muscle. 2014 Feb 1;4(1):4. doi: 10.1186/2044-5040-4-4. Skelet Muscle. 2014. PMID: 24484587 Free PMC article.

4

Pax3-induced expansion enables the genetic correction of dystrophic satellite cells.

Filareto A, Rinaldi F, Arpke RW, Darabi R, Belanto JJ, Toso EA, Miller AZ, Ervasti JM, McIvor RS, Kyba M, Perlingeiro RC. Filareto A, et al. Among authors: toso ea. Skelet Muscle. 2015 Oct 26;5:36. doi: 10.1186/s13395-015-0061-7. eCollection 2015. Skelet Muscle. 2015. PMID: 26504514 Free PMC article.

5

DNA-binding sequence specificity of DUX4.

Zhang Y, Lee JK, Toso EA, Lee JS, Choi SH, Slattery M, Aihara H, Kyba M. Zhang Y, et al. Among authors: toso ea. Skelet Muscle. 2016 Jan 28;6:8. doi: 10.1186/s13395-016-0080-z. eCollection 2016. Skelet Muscle. 2016. PMID: 26823969 Free PMC article.

6

Transcriptional Inhibitors Identified in a 160,000-Compound Small-Molecule DUX4 Viability Screen.

Choi SH, Bosnakovski D, Strasser JM, Toso EA, Walters MA, Kyba M. Choi SH, et al. Among authors: toso ea. J Biomol Screen. 2016 Aug;21(7):680-8. doi: 10.1177/1087057116651868. Epub 2016 May 31. J Biomol Screen. 2016. PMID: 27245141 Free PMC article.

7

p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy.

Bosnakovski D, Gearhart MD, Toso EA, Recht OO, Cucak A, Jain AK, Barton MC, Kyba M. Bosnakovski D, et al. Among authors: toso ea. Dis Model Mech. 2017 Oct 1;10(10):1211-1216. doi: 10.1242/dmm.030064. Epub 2017 Jul 28. Dis Model Mech. 2017. PMID: 28754837 Free PMC article.

8

The DUX4 homeodomains mediate inhibition of myogenesis and are functionally exchangeable with the Pax7 homeodomain.

Bosnakovski D, Toso EA, Hartweck LM, Magli A, Lee HA, Thompson ER, Dandapat A, Perlingeiro RCR, Kyba M. Bosnakovski D, et al. Among authors: toso ea. J Cell Sci. 2017 Nov 1;130(21):3685-3697. doi: 10.1242/jcs.205427. Epub 2017 Sep 21. J Cell Sci. 2017. PMID: 28935672 Free PMC article.

9

ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction.

Park JM, Seo M, Jung CH, Grunwald D, Stone M, Otto NM, Toso E, Ahn Y, Kyba M, Griffin TJ, Higgins L, Kim DH. Park JM, et al. Autophagy. 2018;14(4):584-597. doi: 10.1080/15548627.2017.1422851. Epub 2018 Feb 21. Autophagy. 2018. PMID: 29313410 Free PMC article.

10

Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression.

Bosnakovski D, Gearhart MD, Toso EA, Ener ET, Choi SH, Kyba M. Bosnakovski D, et al. Among authors: toso ea. Sci Rep. 2018 Nov 16;8(1):16957. doi: 10.1038/s41598-018-35150-8. Sci Rep. 2018. PMID: 30446688 Free PMC article.

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