Lorch U - Search Results

1

Kinetics of anti-SARS-CoV-2 IgG antibody levels and potential influential factors in subjects with COVID-19: A 11-month follow-up study.

Luo H, Camilleri D, Garitaonandia I, Djumanov D, Chen T, Lorch U, Täubel J, Wang D. Luo H, et al. Among authors: lorch u. Diagn Microbiol Infect Dis. 2021 Dec;101(4):115537. doi: 10.1016/j.diagmicrobio.2021.115537. Epub 2021 Sep 9. Diagn Microbiol Infect Dis. 2021. PMID: 34619569 Free PMC article.

2

Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects.

Dixon R, Job S, Oliver R, Tompson D, Wright JG, Maltby K, Lorch U, Taubel J. Dixon R, et al. Among authors: lorch u. Br J Clin Pharmacol. 2008 Sep;66(3):396-404. doi: 10.1111/j.1365-2125.2008.03250.x. Epub 2008 Jul 23. Br J Clin Pharmacol. 2008. PMID: 18662287 Free PMC article. Clinical Trial.

3

Levofloxacin can be used effectively as a positive control in thorough QT/QTc studies in healthy volunteers.

Taubel J, Naseem A, Harada T, Wang D, Arezina R, Lorch U, Camm AJ. Taubel J, et al. Among authors: lorch u. Br J Clin Pharmacol. 2010 Apr;69(4):391-400. doi: 10.1111/j.1365-2125.2009.03595.x. Br J Clin Pharmacol. 2010. PMID: 20406223 Free PMC article. Clinical Trial.

4

Bupivacaine extended release liposome injection does not prolong QTc interval in a thorough QT/QTc study in healthy volunteers.

Naseem A, Harada T, Wang D, Arezina R, Lorch U, Onel E, Camm AJ, Taubel J. Naseem A, et al. Among authors: lorch u. J Clin Pharmacol. 2012 Sep;52(9):1441-7. doi: 10.1177/0091270011419853. Epub 2011 Nov 4. J Clin Pharmacol. 2012. PMID: 22058388 Clinical Trial. No abstract available.

5

The practical application of adaptive study design in early phase clinical trials: a retrospective analysis of time savings.

Lorch U, Berelowitz K, Ozen C, Naseem A, Akuffo E, Taubel J. Lorch U, et al. Eur J Clin Pharmacol. 2012 May;68(5):543-51. doi: 10.1007/s00228-011-1176-3. Epub 2011 Nov 25. Eur J Clin Pharmacol. 2012. PMID: 22116461

6

Repeated supratherapeutic dosing of strontium ranelate over 15 days does not prolong QT(c) interval in healthy volunteers.

Taubel J, Naseem A, Wang D, Arezina R, Lorch U, Camm AJ. Taubel J, et al. Among authors: lorch u. Br J Clin Pharmacol. 2012 Aug;74(2):296-303. doi: 10.1111/j.1365-2125.2012.04190.x. Br J Clin Pharmacol. 2012. PMID: 22283848 Free PMC article. Clinical Trial.

7

Insulin at normal physiological levels does not prolong QT(c) interval in thorough QT studies performed in healthy volunteers.

Taubel J, Lorch U, Ferber G, Singh J, Batchvarov VN, Savelieva I, Camm AJ. Taubel J, et al. Among authors: lorch u. Br J Clin Pharmacol. 2013 Feb;75(2):392-403. doi: 10.1111/j.1365-2125.2012.04376.x. Br J Clin Pharmacol. 2013. PMID: 22775199 Free PMC article. Clinical Trial.

8

Thorough QT study of the effect of oral moxifloxacin on QTc interval in the fed and fasted state in healthy Japanese and Caucasian subjects.

Taubel J, Ferber G, Lorch U, Batchvarov V, Savelieva I, Camm AJ. Taubel J, et al. Among authors: lorch u. Br J Clin Pharmacol. 2014 Jan;77(1):170-9. doi: 10.1111/bcp.12168. Br J Clin Pharmacol. 2014. PMID: 23713767 Free PMC article. Clinical Trial.

9

Analyzing the relationship of QT interval and exposure to nitazoxanide, a prospective candidate for influenza antiviral therapy--A formal TQT study.

Täubel J, Lorch U, Rossignol JF, Ferber G, Camm AJ. Täubel J, et al. Among authors: lorch u. J Clin Pharmacol. 2014 Sep;54(9):987-94. doi: 10.1002/jcph.300. Epub 2014 Apr 15. J Clin Pharmacol. 2014. PMID: 24691901 Clinical Trial.

10

Three steps to writing adaptive study protocols in the early phase clinical development of new medicines.

Lorch U, O'Kane M, Taubel J. Lorch U, et al. BMC Med Res Methodol. 2014 Jun 30;14:84. doi: 10.1186/1471-2288-14-84. BMC Med Res Methodol. 2014. PMID: 24980283 Free PMC article.

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