Knevelman C - Search Results

1

Auto-transduction in lentiviral vector bioprocessing: A quantitative assessment and a novel inhibition strategy.

Williams-Fegredo T, Davies L, Knevelman C, Miskin J, Mitrophanous K, Rafiq QA. Williams-Fegredo T, et al. Among authors: knevelman c. Biotechnol Bioeng. 2024 Sep 8. doi: 10.1002/bit.28834. Online ahead of print. Biotechnol Bioeng. 2024. PMID: 39244694

2

Degradation of specific glycosaminoglycans improves transfection efficiency and vector production in transient lentiviral vector manufacturing processes.

Williams-Fegredo T, Davies L, Knevelman C, Mitrophanous K, Miskin J, Rafiq QA. Williams-Fegredo T, et al. Among authors: knevelman c. Front Bioeng Biotechnol. 2024 Jun 26;12:1409203. doi: 10.3389/fbioe.2024.1409203. eCollection 2024. Front Bioeng Biotechnol. 2024. PMID: 38994127 Free PMC article.

3

Lentiviral vector determinants of anion-exchange chromatography elution heterogeneity.

Pamenter G, Davies L, Lamont C, Rahim D, Knevelman C, Miskin J, Mitrophanous K, Dikicioglu D, Bracewell DG. Pamenter G, et al. Among authors: knevelman c. Biotechnol Bioeng. 2024 Sep;121(9):2936-2951. doi: 10.1002/bit.28766. Epub 2024 Jun 14. Biotechnol Bioeng. 2024. PMID: 38874319

4

Development of novel lipoplex formulation methodologies to improve large-scale transient transfection for lentiviral vector manufacture.

Williams-Fegredo T, Davies L, Knevelman C, Mitrophanous K, Miskin J, Rafiq QA. Williams-Fegredo T, et al. Among authors: knevelman c. Mol Ther Methods Clin Dev. 2024 Apr 26;32(2):101260. doi: 10.1016/j.omtm.2024.101260. eCollection 2024 Jun 13. Mol Ther Methods Clin Dev. 2024. PMID: 38745895 Free PMC article.

5

Time-dependent sorption behavior of lentiviral vectors during anion-exchange chromatography.

Pamenter G, Davies L, Knevelman C, Miskin J, Mitrophanous K, Dikicioglu D, Bracewell DG. Pamenter G, et al. Among authors: knevelman c. Biotechnol Bioeng. 2023 Aug;120(8):2269-2282. doi: 10.1002/bit.28483. Epub 2023 Jun 30. Biotechnol Bioeng. 2023. PMID: 37386920

6

Machine learning and metabolic modelling assisted implementation of a novel process analytical technology in cell and gene therapy manufacturing.

Williams T, Kalinka K, Sanches R, Blanchard-Emmerson G, Watts S, Davies L, Knevelman C, McCloskey L, Jones P, Mitrophanous K, Miskin J, Dikicioglu D. Williams T, et al. Among authors: knevelman c. Sci Rep. 2023 Jan 16;13(1):834. doi: 10.1038/s41598-023-27998-2. Sci Rep. 2023. PMID: 36646795 Free PMC article.

7

Manufacturing a chimpanzee adenovirus-vectored SARS-CoV-2 vaccine to meet global needs.

Joe CCD, Jiang J, Linke T, Li Y, Fedosyuk S, Gupta G, Berg A, Segireddy RR, Mainwaring D, Joshi A, Cashen P, Rees B, Chopra N, Nestola P, Humphreys J, Davies S, Smith N, Bruce S, Verbart D, Bormans D, Knevelman C, Woodyer M, Davies L, Cooper L, Kapanidou M, Bleckwenn N, Pappas D, Lambe T, Smith DC, Green CM, Venkat R, Ritchie AJ, Gilbert SC, Turner R, Douglas AD. Joe CCD, et al. Among authors: knevelman c. Biotechnol Bioeng. 2022 Jan;119(1):48-58. doi: 10.1002/bit.27945. Epub 2021 Nov 15. Biotechnol Bioeng. 2022. PMID: 34585736 Free PMC article.

8

High-throughput screening techniques for rapid PEG-based precipitation of IgG4 mAb from clarified cell culture supernatant.

Knevelman C, Davies J, Allen L, Titchener-Hooker NJ. Knevelman C, et al. Biotechnol Prog. 2010 May-Jun;26(3):697-705. doi: 10.1002/btpr.357. Biotechnol Prog. 2010. PMID: 20014099

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