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Page 1
A prenylated dsRNA sensor protects against severe COVID-19.
Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I, Cameron-Ruiz N, Varjak M, Pinto RM, Lee JY, Iselin L, Palmalux N, Stewart DG, Swingler S, Greenwood EJD, Crozier TWM, Gu Q, Davies EL, Clohisey S, Wang B, Trindade Maranhão Costa F, Freire Santana M, de Lima Ferreira LC, Murphy L, Fawkes A, Meynert A, Grimes G; ISARIC4C Investigators; Da Silva Filho JL, Marti M, Hughes J, Stanton RJ, Wang ECY, Ho A, Davis I, Jarrett RF, Castello A, Robertson DL, Semple MG, Openshaw PJM, Palmarini M, Lehner PJ, Baillie JK, Rihn SJ, Wilson SJ. Wickenhagen A, et al. Among authors: turnbull ml. Science. 2021 Oct 29;374(6567):eabj3624. doi: 10.1126/science.abj3624. Epub 2021 Oct 29. Science. 2021. PMID: 34581622 Free PMC article.
Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20.
Feng J, Wickenhagen A, Turnbull ML, Rezelj VV, Kreher F, Tilston-Lunel NL, Slack GS, Brennan B, Koudriakova E, Shaw AE, Rihn SJ, Rice CM, Bieniasz PD, Elliott RM, Shi X, Wilson SJ. Feng J, et al. Among authors: turnbull ml. J Virol. 2018 Jun 13;92(13):e02140-17. doi: 10.1128/JVI.02140-17. Print 2018 Jul 1. J Virol. 2018. PMID: 29695422 Free PMC article.
TRIM69 Inhibits Vesicular Stomatitis Indiana Virus.
Rihn SJ, Aziz MA, Stewart DG, Hughes J, Turnbull ML, Varela M, Sugrue E, Herd CS, Stanifer M, Sinkins SP, Palmarini M, Wilson SJ. Rihn SJ, et al. Among authors: turnbull ml. J Virol. 2019 Sep 30;93(20):e00951-19. doi: 10.1128/JVI.00951-19. Print 2019 Oct 15. J Virol. 2019. PMID: 31375575 Free PMC article.
A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research.
Rihn SJ, Merits A, Bakshi S, Turnbull ML, Wickenhagen A, Alexander AJT, Baillie C, Brennan B, Brown F, Brunker K, Bryden SR, Burness KA, Carmichael S, Cole SJ, Cowton VM, Davies P, Davis C, De Lorenzo G, Donald CL, Dorward M, Dunlop JI, Elliott M, Fares M, da Silva Filipe A, Freitas JR, Furnon W, Gestuveo RJ, Geyer A, Giesel D, Goldfarb DM, Goodman N, Gunson R, Hastie CJ, Herder V, Hughes J, Johnson C, Johnson N, Kohl A, Kerr K, Leech H, Lello LS, Li K, Lieber G, Liu X, Lingala R, Loney C, Mair D, McElwee MJ, McFarlane S, Nichols J, Nomikou K, Orr A, Orton RJ, Palmarini M, Parr YA, Pinto RM, Raggett S, Reid E, Robertson DL, Royle J, Cameron-Ruiz N, Shepherd JG, Smollett K, Stewart DG, Stewart M, Sugrue E, Szemiel AM, Taggart A, Thomson EC, Tong L, Torrie LS, Toth R, Varjak M, Wang S, Wilkinson SG, Wyatt PG, Zusinaite E, Alessi DR, Patel AH, Zaid A, Wilson SJ, Mahalingam S. Rihn SJ, et al. Among authors: turnbull ml. PLoS Biol. 2021 Feb 25;19(2):e3001091. doi: 10.1371/journal.pbio.3001091. eCollection 2021 Feb. PLoS Biol. 2021. PMID: 33630831 Free PMC article.
The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting.
Shaw AE, Rihn SJ, Mollentze N, Wickenhagen A, Stewart DG, Orton RJ, Kuchi S, Bakshi S, Collados MR, Turnbull ML, Busby J, Gu Q, Smollett K, Bamford CGG, Sugrue E, Johnson PCD, Da Silva AF, Castello A, Streicker DG, Robertson DL, Palmarini M, Wilson SJ. Shaw AE, et al. Among authors: turnbull ml. PLoS Biol. 2021 Sep 7;19(9):e3001352. doi: 10.1371/journal.pbio.3001352. eCollection 2021 Sep. PLoS Biol. 2021. PMID: 34491982 Free PMC article.
In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2.
Szemiel AM, Merits A, Orton RJ, MacLean OA, Pinto RM, Wickenhagen A, Lieber G, Turnbull ML, Wang S, Furnon W, Suarez NM, Mair D, da Silva Filipe A, Willett BJ, Wilson SJ, Patel AH, Thomson EC, Palmarini M, Kohl A, Stewart ME. Szemiel AM, et al. Among authors: turnbull ml. PLoS Pathog. 2021 Sep 17;17(9):e1009929. doi: 10.1371/journal.ppat.1009929. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34534263 Free PMC article.
BTN3A3 evasion promotes the zoonotic potential of influenza A viruses.
Pinto RM, Bakshi S, Lytras S, Zakaria MK, Swingler S, Worrell JC, Herder V, Hargrave KE, Varjak M, Cameron-Ruiz N, Collados Rodriguez M, Varela M, Wickenhagen A, Loney C, Pei Y, Hughes J, Valette E, Turnbull ML, Furnon W, Gu Q, Orr L, Taggart A, Diebold O, Davis C, Boutell C, Grey F, Hutchinson E, Digard P, Monne I, Wootton SK, MacLeod MKL, Wilson SJ, Palmarini M. Pinto RM, et al. Among authors: turnbull ml. Nature. 2023 Jul;619(7969):338-347. doi: 10.1038/s41586-023-06261-8. Epub 2023 Jun 28. Nature. 2023. PMID: 37380775 Free article.
Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity.
Turnbull ML, Wise HM, Nicol MQ, Smith N, Dunfee RL, Beard PM, Jagger BW, Ligertwood Y, Hardisty GR, Xiao H, Benton DJ, Coburn AM, Paulo JA, Gygi SP, McCauley JW, Taubenberger JK, Lycett SJ, Weekes MP, Dutia BM, Digard P. Turnbull ML, et al. J Virol. 2016 Sep 29;90(20):9263-84. doi: 10.1128/JVI.01205-16. Print 2016 Oct 15. J Virol. 2016. PMID: 27489273 Free PMC article.
The genetics of virus particle shape in equine influenza A virus.
Elton D, Bruce EA, Bryant N, Wise HM, MacRae S, Rash A, Smith N, Turnbull ML, Medcalf L, Daly JM, Digard P. Elton D, et al. Among authors: turnbull ml. Influenza Other Respir Viruses. 2013 Dec;7 Suppl 4(Suppl 4):81-9. doi: 10.1111/irv.12197. Influenza Other Respir Viruses. 2013. PMID: 24224823 Free PMC article.
14 results