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The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans.
Das R, Melo JA, Thondamal M, Morton EA, Cornwell AB, Crick B, Kim JH, Swartz EW, Lamitina T, Douglas PM, Samuelson AV. Das R, et al. Among authors: samuelson av. PLoS Genet. 2017 Oct 16;13(10):e1007038. doi: 10.1371/journal.pgen.1007038. eCollection 2017 Oct. PLoS Genet. 2017. PMID: 29036198 Free PMC article.
Homeodomain-interacting protein kinase maintains neuronal homeostasis during normal Caenorhabditis elegans aging and systemically regulates longevity from serotonergic and GABAergic neurons.
Lazaro-Pena MI, Cornwell AB, Diaz-Balzac CA, Das R, Ward ZC, Macoretta N, Thakar J, Samuelson AV. Lazaro-Pena MI, et al. Among authors: samuelson av. bioRxiv [Preprint]. 2023 Jun 14:2023.01.11.523661. doi: 10.1101/2023.01.11.523661. bioRxiv. 2023. Update in: Elife. 2023 Jun 20;12:e85792. doi: 10.7554/eLife.85792. PMID: 36711523 Free PMC article. Updated. Preprint.
The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction.
Cornwell A, Zhang Y, Thondamal M, Johnson DW, Thakar J, Samuelson AV. Cornwell A, et al. Among authors: samuelson av. bioRxiv [Preprint]. 2023 Nov 22:2023.11.22.568222. doi: 10.1101/2023.11.22.568222. bioRxiv. 2023. Update in: Geroscience. 2024 Oct;46(5):4827-4854. doi: 10.1007/s11357-024-01197-x. PMID: 38045350 Free PMC article. Updated. Preprint.
19 results