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Page 1
Case Report: Contrasting BCL2 Upregulation With Venetoclax in a Case of Refractory Lymphomatoid Papulosis and Progressive Chronic Lymphocytic Leukemia.
Guarente V, Martino G, Dorillo E, De Falco F, Rompietti C, Sorcini D, Brogna M, Cardinali V, Ascani S, Marra A, Sportoletti P. Guarente V, et al. Among authors: sorcini d. Front Oncol. 2021 Sep 9;11:729106. doi: 10.3389/fonc.2021.729106. eCollection 2021. Front Oncol. 2021. PMID: 34568060 Free PMC article.
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia.
Baldoni S, Del Papa B, Dorillo E, Aureli P, De Falco F, Rompietti C, Sorcini D, Varasano E, Cecchini D, Zei T, Di Tommaso A, Rosati E, Alexe G, Roti G, Stegmaier K, Di Ianni M, Falzetti F, Sportoletti P. Baldoni S, et al. Among authors: sorcini d. Int J Cancer. 2018 Aug 15;143(4):958-970. doi: 10.1002/ijc.31355. Epub 2018 Mar 23. Int J Cancer. 2018. PMID: 29508386 Free PMC article.
Mutant NPM1 Maintains the Leukemic State through HOX Expression.
Brunetti L, Gundry MC, Sorcini D, Guzman AG, Huang YH, Ramabadran R, Gionfriddo I, Mezzasoma F, Milano F, Nabet B, Buckley DL, Kornblau SM, Lin CY, Sportoletti P, Martelli MP, Falini B, Goodell MA. Brunetti L, et al. Among authors: sorcini d. Cancer Cell. 2018 Sep 10;34(3):499-512.e9. doi: 10.1016/j.ccell.2018.08.005. Cancer Cell. 2018. PMID: 30205049 Free PMC article.
GATA1 epigenetic deregulation contributes to the development of AML with NPM1 and FLT3-ITD cooperating mutations.
Sportoletti P, Celani L, Varasano E, Rossi R, Sorcini D, Rompietti C, Strozzini F, Del Papa B, Guarente V, Spinozzi G, Cecchini D, Bereshchenko O, Haferlach T, Martelli MP, Falzetti F, Falini B. Sportoletti P, et al. Among authors: sorcini d. Leukemia. 2019 Jul;33(7):1827-1832. doi: 10.1038/s41375-019-0399-7. Epub 2019 Feb 12. Leukemia. 2019. PMID: 30755706 Free PMC article. No abstract available.
Decreased NOTCH1 Activation Correlates with Response to Ibrutinib in Chronic Lymphocytic Leukemia.
Del Papa B, Baldoni S, Dorillo E, De Falco F, Rompietti C, Cecchini D, Cantelmi MG, Sorcini D, Nogarotto M, Adamo FM, Mezzasoma F, Silva Barcelos EC, Albi E, Iacucci Ostini R, Di Tommaso A, Marra A, Montanaro G, Martelli MP, Falzetti F, Di Ianni M, Rosati E, Sportoletti P. Del Papa B, et al. Among authors: sorcini d. Clin Cancer Res. 2019 Dec 15;25(24):7540-7553. doi: 10.1158/1078-0432.CCR-19-1009. Epub 2019 Oct 2. Clin Cancer Res. 2019. PMID: 31578228
Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice.
Sportoletti P, Sorcini D, Guzman AG, Reyes JM, Stella A, Marra A, Sartori S, Brunetti L, Rossi R, Papa BD, Adamo FM, Pianigiani G, Betti C, Scialdone A, Guarente V, Spinozzi G, Tini V, Martelli MP, Goodell MA, Falini B. Sportoletti P, et al. Among authors: sorcini d. Leukemia. 2021 Jul;35(7):1949-1963. doi: 10.1038/s41375-020-01075-3. Epub 2020 Nov 6. Leukemia. 2021. PMID: 33159179 Free PMC article.
NOTCH1 inhibition prevents GvHD and maintains GvL effect in murine models.
Baldoni S, Ruggeri L, Del Papa B, Sorcini D, Guardalupi F, Ulbar F, Marra A, Dorillo E, Stella A, Giancola R, Fabi B, Sola R, Ciardelli S, De Falco F, Rompietti C, Adamo FM, Rosati E, Pierini A, Sorrentino C, Sportoletti P, Di Ianni M. Baldoni S, et al. Among authors: sorcini d. Bone Marrow Transplant. 2021 Aug;56(8):2019-2023. doi: 10.1038/s41409-021-01297-8. Epub 2021 Apr 19. Bone Marrow Transplant. 2021. PMID: 33875813 No abstract available.
BCOR gene alterations in hematologic diseases.
Sportoletti P, Sorcini D, Falini B. Sportoletti P, et al. Among authors: sorcini d. Blood. 2021 Dec 16;138(24):2455-2468. doi: 10.1182/blood.2021010958. Blood. 2021. PMID: 33945606 Free PMC article. Review.
NOTCH1 Activation Negatively Impacts on Chronic Lymphocytic Leukemia Outcome and Is Not Correlated to the NOTCH1 and IGHV Mutational Status.
Baldoni S, Del Papa B, De Falco F, Dorillo E, Sorrentino C, Rompietti C, Adamo FM, Nogarotto M, Cecchini D, Mondani E, Silva Barcelos EC, Moretti L, Mameli MG, Fabi B, Sorcini D, Stella A, Giancola R, Guardalupi F, Ulbar F, Plebani S, Guarente V, Rosati E, Di Nicola M, Marchioni M, Di Ianni M, Sportoletti P. Baldoni S, et al. Among authors: sorcini d. Front Oncol. 2021 May 26;11:668573. doi: 10.3389/fonc.2021.668573. eCollection 2021. Front Oncol. 2021. PMID: 34123837 Free PMC article.
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