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How to stomach an epigenetic insult: the gastric cancer epigenome.
Padmanabhan N, Ushijima T, Tan P. Padmanabhan N, et al. Among authors: tan p. Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):467-478. doi: 10.1038/nrgastro.2017.53. Epub 2017 May 17. Nat Rev Gastroenterol Hepatol. 2017. PMID: 28513632 Review.
Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer.
Huang KK, Ramnarayanan K, Zhu F, Srivastava S, Xu C, Tan ALK, Lee M, Tay S, Das K, Xing M, Fatehullah A, Alkaff SMF, Lim TKH, Lee J, Ho KY, Rozen SG, Teh BT, Barker N, Chia CK, Khor C, Ooi CJ, Fock KM, So J, Lim WC, Ling KL, Ang TL, Wong A, Rao J, Rajnakova A, Lim LG, Yap WM, Teh M, Yeoh KG, Tan P. Huang KK, et al. Among authors: tan p, tan alk. Cancer Cell. 2018 Jan 8;33(1):137-150.e5. doi: 10.1016/j.ccell.2017.11.018. Epub 2017 Dec 28. Cancer Cell. 2018. PMID: 29290541 Free article.
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer.
Xing M, Ooi WF, Tan J, Qamra A, Lee PH, Li Z, Xu C, Padmanabhan N, Lim JQ, Guo YA, Yao X, Amit M, Ng LM, Sheng T, Wang J, Huang KK, Anene-Nzelu CG, Ho SWT, Ray M, Ma L, Fazzi G, Lim KJ, Wijaya GC, Zhang S, Nandi T, Yan T, Chang MM, Das K, Isa ZFA, Wu J, Poon PSY, Lam YN, Lin JS, Tay ST, Lee MH, Tan ALK, Ong X, White K, Rozen SG, Beer M, Foo RSY, Grabsch HI, Skanderup AJ, Li S, Teh BT, Tan P. Xing M, et al. Among authors: tan p, tan alk, tan j. J Clin Invest. 2020 Jun 1;130(6):3005-3020. doi: 10.1172/JCI126726. J Clin Invest. 2020. PMID: 32364535 Free PMC article.
Mapping the genomic diaspora of gastric cancer.
Yeoh KG, Tan P. Yeoh KG, et al. Among authors: tan p. Nat Rev Cancer. 2022 Feb;22(2):71-84. doi: 10.1038/s41568-021-00412-7. Epub 2021 Oct 26. Nat Rev Cancer. 2022. PMID: 34702982 Review.
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
Varambally S, Cao Q, Mani RS, Shankar S, Wang X, Ateeq B, Laxman B, Cao X, Jing X, Ramnarayanan K, Brenner JC, Yu J, Kim JH, Han B, Tan P, Kumar-Sinha C, Lonigro RJ, Palanisamy N, Maher CA, Chinnaiyan AM. Varambally S, et al. Among authors: tan p. Science. 2008 Dec 12;322(5908):1695-9. doi: 10.1126/science.1165395. Epub 2008 Nov 13. Science. 2008. PMID: 19008416 Free PMC article.
A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets.
Deng N, Goh LK, Wang H, Das K, Tao J, Tan IB, Zhang S, Lee M, Wu J, Lim KH, Lei Z, Goh G, Lim QY, Tan AL, Sin Poh DY, Riahi S, Bell S, Shi MM, Linnartz R, Zhu F, Yeoh KG, Toh HC, Yong WP, Cheong HC, Rha SY, Boussioutas A, Grabsch H, Rozen S, Tan P. Deng N, et al. Among authors: tan al, tan p, tan ib. Gut. 2012 May;61(5):673-84. doi: 10.1136/gutjnl-2011-301839. Epub 2012 Feb 7. Gut. 2012. PMID: 22315472 Free PMC article.
TP53 genomic status regulates sensitivity of gastric cancer cells to the histone methylation inhibitor 3-deazaneplanocin A (DZNep).
Cheng LL, Itahana Y, Lei ZD, Chia NY, Wu Y, Yu Y, Zhang SL, Thike AA, Pandey A, Rozen S, Voorhoeve PM, Yu Q, Tan PH, Bay BH, Itahana K, Tan P. Cheng LL, et al. Among authors: tan p, tan ph. Clin Cancer Res. 2012 Aug 1;18(15):4201-12. doi: 10.1158/1078-0432.CCR-12-0036. Epub 2012 Jun 6. Clin Cancer Res. 2012. PMID: 22675170 Free article.
4,058 results