van Vugt MATM - Search Results

1

A synthetic lethal screen identifies HDAC4 as a potential target in MELK overexpressing cancers.

Zhou L, Zheng S, Rosas Bringas FR, Bakker B, Simon JE, Bakker PL, Kazemier HG, Schubert M, Roorda M, van Vugt MATM, Chang M, Foijer F. Zhou L, et al. Among authors: van vugt matm. G3 (Bethesda). 2021 Dec 8;11(12):jkab335. doi: 10.1093/g3journal/jkab335. G3 (Bethesda). 2021. PMID: 34550356 Free PMC article.

2

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling.

van Harn T, Foijer F, van Vugt M, Banerjee R, Yang F, Oostra A, Joenje H, te Riele H. van Harn T, et al. Genes Dev. 2010 Jul 1;24(13):1377-88. doi: 10.1101/gad.580710. Epub 2010 Jun 15. Genes Dev. 2010. PMID: 20551164 Free PMC article.

3

Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors.

Huisman C, Wisman GB, Kazemier HG, van Vugt MA, van der Zee AG, Schuuring E, Rots MG. Huisman C, et al. Mol Oncol. 2013 Jun;7(3):669-79. doi: 10.1016/j.molonc.2013.02.017. Epub 2013 Mar 5. Mol Oncol. 2013. PMID: 23522960 Free PMC article.

4

A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity.

Heijink AM, Blomen VA, Bisteau X, Degener F, Matsushita FY, Kaldis P, Foijer F, van Vugt MA. Heijink AM, et al. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15160-5. doi: 10.1073/pnas.1505283112. Epub 2015 Nov 23. Proc Natl Acad Sci U S A. 2015. PMID: 26598692 Free PMC article.

5

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells.

Schoonen PM, Talens F, Stok C, Gogola E, Heijink AM, Bouwman P, Foijer F, Tarsounas M, Blatter S, Jonkers J, Rottenberg S, van Vugt MATM. Schoonen PM, et al. Among authors: van vugt matm. Nat Commun. 2017 Jul 17;8:15981. doi: 10.1038/ncomms15981. Nat Commun. 2017. PMID: 28714471 Free PMC article.

6

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.

Zomerman WW, Plasschaert SLA, Conroy S, Scherpen FJ, Meeuwsen-de Boer TGJ, Lourens HJ, Guerrero Llobet S, Smit MJ, Slagter-Menkema L, Seitz A, Gidding CEM, Hulleman E, Wesseling P, Meijer L, van Kempen LC, van den Berg A, Warmerdam DO, Kruyt FAE, Foijer F, van Vugt MATM, den Dunnen WFA, Hoving EW, Guryev V, de Bont ESJM, Bruggeman SWM. Zomerman WW, et al. Among authors: van vugt matm, van kempen lc, van den berg a. Cell Rep. 2018 Mar 20;22(12):3206-3216. doi: 10.1016/j.celrep.2018.02.089. Cell Rep. 2018. PMID: 29562177 Free article.

7

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells.

van Gijn SE, Wierenga E, van den Tempel N, Kok YP, Heijink AM, Spierings DCJ, Foijer F, van Vugt MATM, Fehrmann RSN. van Gijn SE, et al. Among authors: van vugt matm, van den tempel n. Oncogene. 2019 Feb;38(6):852-867. doi: 10.1038/s41388-018-0470-2. Epub 2018 Sep 3. Oncogene. 2019. PMID: 30177840 Free PMC article.

8

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells.

Schoonen PM, Kok YP, Wierenga E, Bakker B, Foijer F, Spierings DCJ, van Vugt MATM. Schoonen PM, et al. Among authors: van vugt matm. Mol Oncol. 2019 Nov;13(11):2422-2440. doi: 10.1002/1878-0261.12573. Epub 2019 Oct 21. Mol Oncol. 2019. PMID: 31529615 Free PMC article.

9

The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma.

Bočkaj I, Martini TEI, de Camargo Magalhães ES, Bakker PL, Meeuwsen-de Boer TGJ, Armandari I, Meuleman SL, Mondria MT, Stok C, Kok YP, Bakker B, Wardenaar R, Seiler J, Broekhuis MJC, van den Bos H, Spierings DCJ, Ringnalda FCA, Clevers H, Schüller U, van Vugt MATM, Foijer F, Bruggeman SWM. Bočkaj I, et al. Among authors: van vugt matm, van den bos h. PLoS Genet. 2021 Nov 9;17(11):e1009868. doi: 10.1371/journal.pgen.1009868. eCollection 2021 Nov. PLoS Genet. 2021. PMID: 34752469 Free PMC article.

10

cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers.

Hong C, Schubert M, Tijhuis AE, Requesens M, Roorda M, van den Brink A, Ruiz LA, Bakker PL, van der Sluis T, Pieters W, Chen M, Wardenaar R, van der Vegt B, Spierings DCJ, de Bruyn M, van Vugt MATM, Foijer F. Hong C, et al. Among authors: van vugt matm, van den brink a, van der sluis t, van der vegt b. Nature. 2022 Jul;607(7918):366-373. doi: 10.1038/s41586-022-04847-2. Epub 2022 Jun 15. Nature. 2022. PMID: 35705809

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