Bakker PL - Search Results

1

A synthetic lethal screen identifies HDAC4 as a potential target in MELK overexpressing cancers.

Zhou L, Zheng S, Rosas Bringas FR, Bakker B, Simon JE, Bakker PL, Kazemier HG, Schubert M, Roorda M, van Vugt MATM, Chang M, Foijer F. Zhou L, et al. Among authors: bakker pl. G3 (Bethesda). 2021 Dec 8;11(12):jkab335. doi: 10.1093/g3journal/jkab335. G3 (Bethesda). 2021. PMID: 34550356 Free PMC article.

2

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.

Foijer F, Xie SZ, Simon JE, Bakker PL, Conte N, Davis SH, Kregel E, Jonkers J, Bradley A, Sorger PK. Foijer F, et al. Among authors: bakker pl. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13427-32. doi: 10.1073/pnas.1400892111. Epub 2014 Sep 2. Proc Natl Acad Sci U S A. 2014. PMID: 25197064 Free PMC article.

3

FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.

Macedo JC, Vaz S, Bakker B, Ribeiro R, Bakker PL, Escandell JM, Ferreira MG, Medema R, Foijer F, Logarinho E. Macedo JC, et al. Among authors: bakker pl. Nat Commun. 2018 Jul 19;9(1):2834. doi: 10.1038/s41467-018-05258-6. Nat Commun. 2018. PMID: 30026603 Free PMC article.

4

Altering microtubule dynamics is synergistically toxic with spindle assembly checkpoint inhibition.

Schukken KM, Lin YC, Bakker PL, Schubert M, Preuss SF, Simon JE, van den Bos H, Storchova Z, Colomé-Tatché M, Bastians H, Spierings DC, Foijer F. Schukken KM, et al. Among authors: bakker pl. Life Sci Alliance. 2020 Jan 24;3(2):e201900499. doi: 10.26508/lsa.201900499. Print 2020 Feb. Life Sci Alliance. 2020. PMID: 31980556 Free PMC article.

5

Acute systemic loss of Mad2 leads to intestinal atrophy in adult mice.

Schukken KM, Zhu Y, Bakker PL, Koster MH, Harkema L, Youssef SA, de Bruin A, Foijer F. Schukken KM, et al. Among authors: bakker pl. Sci Rep. 2021 Jan 8;11(1):68. doi: 10.1038/s41598-020-80169-5. Sci Rep. 2021. PMID: 33420244 Free PMC article.

6

The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma.

Bočkaj I, Martini TEI, de Camargo Magalhães ES, Bakker PL, Meeuwsen-de Boer TGJ, Armandari I, Meuleman SL, Mondria MT, Stok C, Kok YP, Bakker B, Wardenaar R, Seiler J, Broekhuis MJC, van den Bos H, Spierings DCJ, Ringnalda FCA, Clevers H, Schüller U, van Vugt MATM, Foijer F, Bruggeman SWM. Bočkaj I, et al. Among authors: bakker pl. PLoS Genet. 2021 Nov 9;17(11):e1009868. doi: 10.1371/journal.pgen.1009868. eCollection 2021 Nov. PLoS Genet. 2021. PMID: 34752469 Free PMC article.

7

cGAS-STING drives the IL-6-dependent survival of chromosomally instable cancers.

Hong C, Schubert M, Tijhuis AE, Requesens M, Roorda M, van den Brink A, Ruiz LA, Bakker PL, van der Sluis T, Pieters W, Chen M, Wardenaar R, van der Vegt B, Spierings DCJ, de Bruyn M, van Vugt MATM, Foijer F. Hong C, et al. Among authors: bakker pl. Nature. 2022 Jul;607(7918):366-373. doi: 10.1038/s41586-022-04847-2. Epub 2022 Jun 15. Nature. 2022. PMID: 35705809

8

Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum.

Bočkaj I, Martini TEI, Smit MJ, Armandari I, Bakker B, Wardenaar R, Meeuwsen-de Boer TGJ, Bakker PL, Spierings DCJ, Hoving EW, Guryev V, Foijer F, Bruggeman SWM. Bočkaj I, et al. Among authors: bakker pl. Int J Mol Sci. 2022 Aug 30;23(17):9852. doi: 10.3390/ijms23179852. Int J Mol Sci. 2022. PMID: 36077248 Free PMC article.

9

Neurodegeneration-associated protein VAPB regulates proliferation in medulloblastoma.

Faria Assoni A, Giove Mitsugi T, Wardenaar R, Oliveira Ferreira R, Farias Jandrey EH, Machado Novaes G, Fonseca de Oliveira Granha I, Bakker P, Kaid C, Zatz M, Foijer F, Keith Okamoto O. Faria Assoni A, et al. Sci Rep. 2023 Nov 9;13(1):19481. doi: 10.1038/s41598-023-45319-5. Sci Rep. 2023. PMID: 37945695 Free PMC article.

10

Adaptation of Spodoptera exigua larvae to plant proteinase inhibitors by induction of gut proteinase activity insensitive to inhibition.

Jongsma MA, Bakker PL, Peters J, Bosch D, Stiekema WJ. Jongsma MA, et al. Among authors: bakker pl. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):8041-5. doi: 10.1073/pnas.92.17.8041. Proc Natl Acad Sci U S A. 1995. PMID: 7644535 Free PMC article.

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