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Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential.
Meyer B, Chiaravalli J, Gellenoncourt S, Brownridge P, Bryne DP, Daly LA, Grauslys A, Walter M, Agou F, Chakrabarti LA, Craik CS, Eyers CE, Eyers PA, Gambin Y, Jones AR, Sierecki E, Verdin E, Vignuzzi M, Emmott E. Meyer B, et al. Among authors: sierecki e. Nat Commun. 2021 Sep 21;12(1):5553. doi: 10.1038/s41467-021-25796-w. Nat Commun. 2021. PMID: 34548480 Free PMC article.
Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling.
Ve T, Vajjhala PR, Hedger A, Croll T, DiMaio F, Horsefield S, Yu X, Lavrencic P, Hassan Z, Morgan GP, Mansell A, Mobli M, O'Carroll A, Chauvin B, Gambin Y, Sierecki E, Landsberg MJ, Stacey KJ, Egelman EH, Kobe B. Ve T, et al. Among authors: sierecki e. Nat Struct Mol Biol. 2017 Sep;24(9):743-751. doi: 10.1038/nsmb.3444. Epub 2017 Jul 31. Nat Struct Mol Biol. 2017. PMID: 28759049 Free PMC article.
64 results